Sökning: "Glycosphingolipids"

Visar resultat 21 - 25 av 25 avhandlingar innehållade ordet Glycosphingolipids.

  1. 21. Biomolecular interactions at model interfaces : a self-assembled monolayer approach

    Författare :Sofia Svedhem; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The overall aim of this thesis has been to explore the use of self-assembled monolayers (SAMs) in model studies of biomolecular binding at interfaces. Molecular details of interfaces are difficult to address experimentally, and in spite of the fact that interactions in the living system commonly occur at interfaces, e.g. LÄS MER

  3. 22. Is modulation of glucocerebrosidase a viable new treatment for Parkinson's disease?

    Författare :Mark Zurbruegg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Parkinson's disease is the second most prevalent neurodegenerative disorder. There are currently no treatments that cure Parkinson’s disease (PD) or slow its progression. There is therefore an urgent need for novel treatments. It was recently discovered that patients with mutations in GBA1 are more likely to develop PD. LÄS MER

  4. 23. Elucidating Genetic and Biochemical Aspects of the P1 and Sda Carbohydrate Histo-Blood Group Antigens

    Författare :Linn Stenfelt; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood Group; P1 antigen; Sda antigen; A4GALT; B3GALNT2; glycosyltransferase; red blood cell; transfusion medicine;

    Sammanfattning : Human histo-blood groups are inherited polymorphic variants that occur in the molecular structures on the humanred blood cell (RBC) surface. Introducing foreign RBCs into a recipient lacking an antigen may activate the humoraldefence leading to a hemolytic transfusion reaction. LÄS MER

  5. 24. Mucosal receptors involved in pathogen recognition and host defence

    Författare :Majlis Svensson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nefrologi; Urologi; nephrology; Urology; Infections; Infektioner;

    Sammanfattning : Urinary tract infection is the most common infection in man. P fimbriae are virulence factors of uro-pathogenic Escherichia coli. They are expressed by 70-90 % of acute pyelonephritis isolates and up to 100% of the most virulent isolates that cause bacteremia. LÄS MER

  7. 25. The involvement of gangliosides in growth and migration of human glioblastoma cells

    Författare :Kristina Hedberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gangliosides synthesis; Ganglioside expression; Glioblastoma; Migration; Proliferation; Cell culture systems; Xenograft model;

    Sammanfattning : Human glioblastoma is a primary brain tumour with a bad prognosis. One major contributing factor is that the tumour grows in an infiltrative way. Single tumour cells, undetectable with today's techniques, invade the brain and escape therapy. LÄS MER