Sökning: "Fysik med inriktning mot biofysik"
Visar resultat 11 - 15 av 16 avhandlingar innehållade orden Fysik med inriktning mot biofysik.
11. Ultrafast Structural and Electron Dynamics in Soft Matter Exposed to Intense X-ray Pulses
Sammanfattning : Investigations of soft matter using ultrashort high intensity pulses have been made possible through the advent of X-ray free-electrons lasers. The last decade has seen the development of a new type of protein crystallography where femtosecond dynamics can be studied, and single particle imaging with atomic resolution is on the horizon. LÄS MER
12. Simulations of Biomolecular Fragmentation and Diffraction with Ultrafast X-ray Lasers
Sammanfattning : Studies of biomolecules have recently seen substantial developments. New X-ray lasers allow for high-resolution imaging of protein crystals too small for conventional X-ray crystallography. Even structures of single particles have been determined at lower resolutions with these new sources. LÄS MER
13. Alexandria: A General Drude Polarizable Force Field with Spherical Charge Density
Sammanfattning : Molecular-mechanical (MM) force fields are mathematical functions that map the geometry of a molecule to its associated energy. MM force fields have been extensively used for an atomistic view into the dynamic and thermodynamics of large molecular systems in their condensed phase. LÄS MER
14. Towards Fast and Robust Algorithms in Flash X-ray single-particle Imaging
Sammanfattning : Modern X-ray Free Electron Laser (XFEL) technology provides the possibility to acquire a large number of diffraction patterns from individual biological nano-particles, including proteins, viruses, and DNA. Ideally, the collected data frames are high-quality single-particle diffraction patterns. LÄS MER
15. Polymer and Protein Physics : Simulations of Interactions and Dynamics
Sammanfattning : Proteins can, without any exaggeration, be called the "building blocks of life". Their physical properties depend not only on the chemical structure but also on their geometric shape. In this thesis, I investigate protein geometry using several different methods.We start with a coarse-graining model to study the general behavior of polymers. LÄS MER