Sökning: "Carotid lesion"

Visar resultat 6 - 10 av 17 avhandlingar innehållade orden Carotid lesion.

  1. 6. Identification of inflammatory genes involved in the pathogenesis of human and experimental atherosclerosis

    Författare :Hanna E Agardh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atherosclerosis is a chronic systemic inflammatory disease of large and medium sized arteries, developing slowly and silently over decades. The disease is usually not apparent until occurrence of a sudden clinical symptom, such as myocardial infarction (MI) or stroke. LÄS MER

  3. 7. Bridging innate and adaptive immunity in cardiovascular disease

    Författare :Glykeria Karadimou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cardiovascular disease is the leading cause of death and morbidity in the world. Myocardial infarction and stroke constitute the main manifestations of atherosclerosis that lead to the majority of cardiovascular events. Calcific aortic valve stenosis is the most common valve pathology. LÄS MER

  4. 8. Immune mechanisms behind plaque vulnerability : experimental and clinical studies

    Författare :Olga Ovchinnikova; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Physical disruption of atherosclerotic plaques causes many acute thrombotic complications such as myocardial infarction and stroke. The resistance of the atherosclerotic plaque to disruption depends in part on the integrity of its fibrous cap, which prevents contact between the highly thrombogenic lipid core and the circulating blood. LÄS MER

  5. 9. Cardiovascular role of PDGF-B in development and disease. Studies in genetically engineered mice

    Författare :Henrik Nyström; Göteborgs universitet; []
    Nyckelord :atherosclerosis; cardiovascular disease; cell retention; in vivo physiology; neointimal hyperplasia; PDGF; transgenic mice; vascular function; vascular smooth muscle cell;

    Sammanfattning : Platelet-derived growth factor B (PDGF-B) is vital for microvascular development, and retention of PDGF-B to extracellular matrix (ECM) is important in this process. However, the role and source of PDGF-B in development of macrovascular function is disputed. LÄS MER

  7. 10. Filamin A in Cardiovascular Remodeling

    Författare :Sashidar Bandaru; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Filamin A; Cardiovascular remodelling;

    Sammanfattning : Filamin A (FLNA) is a large actin-binding cytoskeletal protein that stabilizes actin networks and integrates them with cell membranes. FLNA is therefore important for cell motility and organ development. LÄS MER