Sökning: "Carmen Fernández"
Visar resultat 6 - 10 av 11 avhandlingar innehållade orden Carmen Fernández.
6. Maturation of humoral immune responses : Studies on the effects of antigen type, apoptosis and age
Sammanfattning : The humoral immune response is dependent on the formation of antibodies. Antibodies are produced by terminally differentiated B cells, plasma cells. Plasma cells are generated either directly from antigen challenged B cells, memory cells or from cells that have undergone the germinal center (GC) reaction. LÄS MER
7. Heat shock proteins as vaccine adjuvants
Sammanfattning : New efficient vaccines against infectious diseases are in demand. Some important factors impeding the vaccine development are the poor immunogenicity and the MHC restriction of the immune responses to a number of antigens. LÄS MER
8. Diagnostic biomarkers and improved vaccination against mycobacterial infection
Sammanfattning : Tuberculosis (TB) remains one of the world’s most serious infectious diseases. It is estimated that a third of the world’s population is latently infected and 8 million new cases are recorded each year. LÄS MER
9. Mucosal immunity against mycobacterial infection
Sammanfattning : This thesis aimed to the identification of immune biomarkers of mycobacterial infection for better diagnosis of tuberculosis (TB) and also focused on new vaccination strategies with a particular emphasis on the immune responses in the respiratory tract using murine models. Since the lung is the natural habitat for the M. LÄS MER
10. Mucosal immunity in the respiratory tract : The role of IgA in protection against intracellular pathogens
Sammanfattning : The lungs and upper airways are mucosal surfaces that are common site for infection with an enormous variety of inhaled pathogens. Therefore, induction of immune responses in the respiratory tract is crucial for protection against respiratory diseases. One of the pathogens infecting the host via the respiratory tract is Mycobacterium Tuberculosis. LÄS MER