Sökning: "CD163"

Visar resultat 1 - 5 av 14 avhandlingar innehållade ordet CD163.

  1. 1. The impact of Wnt5a signaling and tumor associated macrophages in breast cancer

    Författare :Catharina Hagerling; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Wnt5a; E-cadherin; B-catenin; migration; invasion; turnor associated macrophages; CD163; CD68; turnor stroma;

    Sammanfattning : Breast cancer is the most common cancer among women worldwide with approximately 1.150.000 new cases each year and accounting for over 400.000 deaths per year. LÄS MER

  2. 2. Fat mass, adipokines and clinical complications of chronic kidney disease

    Författare :Jonas Axelsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Chronic kidney disease; end-stage renal disease; insulin resistance; inflammation; cardiovascular disease; adipokines; leptin; epoetin; resistin; visfatin; AHSG; CD163; outcome.;

    Sammanfattning : Patients with chronic kidney disease (CKD), irrespective of initial etiology, have a risk of cardiovascular morbidity (CVD) and mortality that is many-fold higher than that of a similar person without CKD. While traditional risk factors, such as hyperlipidemia, certainly contribute, these factors cannot by themselves explain the burden of CVD. LÄS MER

  3. 3. Macrophage antigen expression in breast and colorectal cancers : A consequence of macrophage - tumour cell fusion?

    Författare :Ivan Shabo; Joar Svanvik; Bengt Gustavsson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Carcinogenesis is a sophisticated biological process consisting of a series of progressive changes in somatic cells from premalignant to malignant phenotype. Despite the vast information available about cancer cells, the origin of cancer and cause of metastasis still remain enigmatic. LÄS MER

  4. 4. Immune regulation at the fetal‐maternal interface with focus on decidual macrophages

    Författare :Judit Svensson‐Arvelund; Jan Ernerudh; Maria Jenmalm; Göran Berg; Siamon Gordon; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : A successful pregnancy requires that the maternal immune system adapts to tolerate the semi-allogeneic fetal-placental unit. This adaptation mainly occurs locally, i.e. at the fetal-maternal interface, where fetal-derived tissues come into close contact with maternal cells in the uterine endometrium (called decidua during pregnancy). LÄS MER

  5. 5. Immune regulation at the foetal-maternal interface; implications for healthy and complicated pregnancies

    Författare :Robert Lindau; Jan Ernerudh; Maria Jenmalm; Kristina Nilsson-Ekdahl; Petra Arck; Linköpings universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : For a successful pregnancy, the maternal immune system must acquire tolerance towards the paternal antigens present in the semi-allogeneic foetus. This tolerance is mainly established locally at the foetal-maternal interface, where foetally-derived trophoblasts invade the maternal endometrium (called decidua during pregnancy) and come in close proximity to maternal immune cells. LÄS MER