Sökning: "CD163"

Visar resultat 6 - 10 av 19 avhandlingar innehållade ordet CD163.

  1. 6. Immune regulation at the foetal-maternal interface; implications for healthy and complicated pregnancies

    Författare :Robert Lindau; Jan Ernerudh; Maria Jenmalm; Kristina Nilsson-Ekdahl; Petra Arck; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : For a successful pregnancy, the maternal immune system must acquire tolerance towards the paternal antigens present in the semi-allogeneic foetus. This tolerance is mainly established locally at the foetal-maternal interface, where foetally-derived trophoblasts invade the maternal endometrium (called decidua during pregnancy) and come in close proximity to maternal immune cells. LÄS MER

  3. 7. The immune microenvironment in mantle cell lymphoma : Targeted liquid and spatial proteomic analyses

    Författare :Lavanya Lokhande; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mantle cell lymphoma MCL ; proteomic analyses; spatial analysis; Biomarker discovery; immune microenviroment; serum proteomics;

    Sammanfattning : The complex interplay of the tumour and immune cells affects tumour growth, progression, and response to treatment. Restorationof effective immune response forms the basis of onco-immunology, which further enabled the development of immunotherapy. LÄS MER

  4. 8. Mutation and immune profiling of non-small cell lung cancer

    Författare :Linnéa La Fleur; Johan Botling; Fernando López-Ríos; Uppsala universitet; []
    Nyckelord :Non-small cell lung cancer; Tumor microenvironment; Tumor-associated macrophages; Immune infiltrates; PD-L1; Mutation patterns; Immune therapy; MARCO; TP53; STK11; KRAS;

    Sammanfattning : Several novel therapies that target molecular alterations and immune checkpoints in lung cancer have been introduced in the last decade. Still, only a minority of patients obtain long term disease control and overall survival remains poor. LÄS MER

  5. 9. Aplastic anemia - a population-based study of epidemiology, treatment, and prognostic factors

    Författare :Krista Vaht; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aplastic anemia;

    Sammanfattning : Background and aims. Aplastic anemia (AA) is a rare but life-threatening disease. The introduction of immunosuppressive treatment (IST) and hematopoietic stem cell transplantation (HSCT) has considerably improved the outcome of patients with AA. However, modern-day population-based data are limited. LÄS MER

  7. 10. Spatial immune analyses in clinical cancer tissue

    Författare :Max Backman; Patrick Micke; Fredrik Pontén; Johan Botling; Kurt Schalper; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immune landscape; non-small cell lung cancer; immune cells; multiplex immunofluorescence; spatial analysis; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Cancer is a leading cause of premature death and lung cancer is the deadliest cancer type, with non-small cell lung cancer (NSCLC) representing 85% of lung cancer cases. Despite promising development in cancer treatment in recent decades, overall prognosis is poor. LÄS MER