Sökning: "C1 esterase inhibitor"

Hittade 3 avhandlingar innehållade orden C1 esterase inhibitor.

  1. 1. Novel treatments of glioblastoma in experimental models

    Författare :Karolina Förnvik; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Experimental glioma models; Glioblastoma; Complement system; C1 esterase inhibitor; ITPP; CRP; Glioma cells;

    Sammanfattning : One of the major problems with malignant brain tumours, such as glioblastoma multiforme, is that despite being able to remove the major bulk of the tumour through surgery and treating the patients with chemotherapy and radiotherapy, we know that tumour cells have already spread throughout the brain. Furthermore, we now know that the glioblastoma cells effectively suppress the patients’ own anti-tumour response. LÄS MER

  3. 2. Mechanism and therapy of hereditary angioedema typ III and role of the contact system in inflammatory diseases

    Författare :Jenny Björkqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Combinations of proinflammatory and procoagulant reactions are associated with a variety of disorders affecting the cardiovascular system. Vascular leakage contributes to the pathology of conditions such as, sepsis, allergy and anaphylactic reactions. LÄS MER

  4. 3. Inhibition of the plasma contact system on endpoint immobilized heparin and human endothelium

    Författare :Javier Augusto Sánchez Saavedra; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Contact activation system; FXII; prokallikrein; antithrombin; specific AT-binding site; immobilized heparin; heparan sulphate; endothelium;

    Sammanfattning : When blood is exposed to foreign materials or injured tissue, several defense systems are activated. The contact with an artificial surface leads to activation of FXII, the first proenzyme of the plasma contact activation system, with concomitant triggering of the intrinsic coagulation and also the fibrinolytic-, kallikrein- and complement systems. LÄS MER