Sökning: "Björn Schilström"

Hittade 1 avhandling innehållade orden Björn Schilström.

1. 1. Nicotinic effects on midbrain dopamine neurons : a dual mechanism of action

   Författare :Björn Schilström; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :nicotine; dopamine; ventral tegmental area; glutamate; microdialysis; Fos expression; NMDA receptor; presynaptic;

   Sammanfattning : The neurons of the mesocorticolimbic dopamine system are located in the ventral tegmental area (VTA) in the mesencephalon and send their projections to forebrain structures, such as the prefrontal cortex, the amygdala and the nucleus accumbens. The dopamine system is important in regulating mood and motivation as well as cognitive function and appear to be primarily involved in drug dependence, since most drugs abused by man stimulate this system. LÄS MER