Sökning: "Axotomy"

Visar resultat 21 - 25 av 40 avhandlingar innehållade ordet Axotomy.

  1. 21. On VEGF and related factors in neurotrauma

    Författare :Mattias Sköld; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Spinal cord; brain; motoneuron; VEGF; VEGFR1; VEGFR2; Np1; Np2; Sema3A; HIF1alpha;

    Sammanfattning : At present, there is no cure for traumatic spinal cord and brain injuries. Therapies in use have only modest effect on outcome. Therefore, the need to better understand the biology of traumatic CNS injuries, making development of new therapies possible, is huge. LÄS MER

  3. 22. Neuroprotection and axonal regeneration after peripheral nerve injury

    Författare :Dag Welin; Lev N. Novikov; Lars B. Dahlin; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dorsal root ganglion; Motoneuron; Axonal reaction; Peripheral nerve injury; Nerve regeneration; N-acetylcysteine; Hand surgery; Handkirurgi; Anatomy; Anatomi; anatomi; Human Anatomy; handkirurgi; hand surgery;

    Sammanfattning : Following microsurgical reconstruction of injured peripheral nerves, severed axons are able to undergo spontaneous regeneration. However, the functional result is always unsatisfactory with poor sensory recovery and reduced motor function. LÄS MER

  4. 23. Expression and regulation of neuronal messenger molecules : focus on the NO-cGMP pathway and galanin in autonomic and sensory neurons

    Författare :Kristina Holmberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :adrenal gland; autonomic ganglia; cGMP; dorsal root ganglion; galanin; immunohistochemistry; in situ hybridization; nerve growth factor; neuropeptides; nitric oxide synthase; sodium nitroprusside; transgenic mice;

    Sammanfattning : The autonomic nervous system consists of the sympathetic, parasympathetic and enteric divisions. The sympathetic pre- and paravertebral neurons are in principle of noradrenergic phenotype. However, originally pharmacological experiments indicated that sympathetic fibers projecting to the sweat glands are cholinergic. LÄS MER

  5. 24. Cell-matrix interactions in neuronal regeneration : focus on integrins and laminins

    Författare :Stefan Plantman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The central and peripheral nervous system (CNS and PNS, respectively) differ in their ability to regenerate after injury. This difference has been attributed both to intrinsic differences in the properties of the neurons and to the extracellular environment. LÄS MER

  7. 25. Regulation of cardiorespiratory homeostasis in adult and developing rat by catecholamines : effects of hypoxia

    Författare :Julie Peyronnet; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :hypoxia; brainstem; catecholamines; chemoreflexe; ventilation; perinatal rat;

    Sammanfattning : The aims of the present study were as follow 1) to characterise the neuroplasticity of sympathetic ganglia in the adult rat, after exposure to long-term hypoxia and/or axotomy of the superior cervical ganglion (SCG). The cellular distributions of TH (tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis) and VIP (vasointestinal peptide, which enhances the expression of TH) were examined. LÄS MER