Sökning: "gut barrier"

Visar resultat 1 - 5 av 59 avhandlingar innehållade orden gut barrier.

  1. 1. Gut microbiota to counteract metabolic disorders and neuroinflammation : Impact of dietary factors and their potential to prevent Alzheimer’s disease

    Författare :Nittaya Marungruang; Avdelningen för livsmedel och läkemedel; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; gut microbiota; metabolic disorders; inflammation; neuroinflammation; lingonberries; dietary fibre; gut barrier; blood-brain barrier;

    Sammanfattning : Alzheimer’s disease (AD) is the most common form of dementia. Increased accumulations of senile plaques and tangles are the known neuropathological hallmarks of AD. However, the exact triggers for such protein accumulations, leading to cognitive impairment and important morphological alteration in AD, are still elusive. LÄS MER

  3. 2. Gut Feelings - From Brain to Gut and from Lumen to Gut

    Författare :Xiaowen Cheng; Neurogastroenterologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Enteric nervous system; cerebral ischemia; galectine-3; tuft cell; CGRP; CCK; GLP-1; 5HT; PYY;

    Sammanfattning : Part 1: From Brain to GutThe brain is an organ with a high energy requirement. To meet this demand, the brain needs a continuous and well-regulated blood supply. In situations where the brain, or parts of the brain, does not receive sufficient blood flow injury arise. LÄS MER

  4. 3. The role of the gut microbiota in central energy balance regulation

    Författare :Christina Heiss; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gut microbiota; energy balance regulation; hypothalamic inflammation; astrocytes; blood-brain barrier; neurons;

    Sammanfattning : The gut microbiota can affect development and metabolism in the host. Today, much is still unknown regarding the effects of the gut microbiota on central energy balance regulation. We used mouse models to determine the role of the gut microbiota in diet- induced hypothalamic inflammation as well as in hypothalamic development. LÄS MER

  5. 4. Whole grain cereal products and baseline gut microbiota composition in metabolic and appetite regulation in healthy humans - Emphasizing rye and barley

    Författare :Jonna Sandberg; Avdelningen för livsmedel och läkemedel; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; Type 2 Diabetes; Whole grain; Rye; Barley; Gut microbiota; Glucose regulation; Gut fermentation;

    Sammanfattning : The prevalence of obesity, type 2 diabetes (T2D) and cardiovascular disease (CVD) is increasing continuously worldwide. These metabolic diseases are associated with many health issues, including increased risk of depression and cognitive impairment. Whole grain (WG) has shown potential to prevent obesity, T2D and CVD. LÄS MER

  7. 5. Development of the gastrointestinal tract in young mammals : Effects of enteral provocation with protease or phytohaemagglutinin in neonatal rats

    Författare :Ester Arevalo Sureda; Funktionell zoologi; []
    Nyckelord :gut; Intestine; Pancreas; development; precocious; protease; PHA; enterocytes; permeability; endocytosis; IgG; FcRn; Blimp1; T-lymphocyte; passive immunity; altricial; neonatal; suckling; athymic; rat; immunohistochemistry IHC ;

    Sammanfattning : The rat, as an altritial species, is born with an immature gastrointestinal tract and intestinal barrier function, which is highly absorptive to milk-borne bioactive molecules that can pass undigested and reach the general circulation of the suckling newborn. This passage occurs by the neonatal-Fc-receptor (FcRn) binding and trancytosis of immunoglobulin G in the proximal small intestine (SI) and by the highly endocytic vacuolated enterocytes non-selectively in the distal SI. LÄS MER