Sökning: "CGRP"
Visar resultat 1 - 5 av 81 avhandlingar innehållade ordet CGRP.
1. Distribution of CGRP and CGRP receptor in the trigeminovascular system and CNS
Sammanfattning : Calcitonin gene-related peptide (CGRP) has a key role in the pathophysiology of migraine and is associated with activation of the trigeminovascular system. Recently, CGRP receptor antagonists have been developed with clinical efficacy. LÄS MER
2. Brain Stem Involvement in Immune and Aversive Challenge
Sammanfattning : Activation of the immune system by e.g. bacteria induces the acute-phase-response and sickness behaviour. The latter encompasses among other things fever, lethargy, anorexia and hyperalgesia. LÄS MER
3. Peripheral Regulation of Pain and Itch
Sammanfattning : Pain and itch are diverse sensory modalities, transmitted by the somatosensory nervous system. Stimuli such as heat, cold, mechanical pain and itch can be transmitted by different neuronal populations, which show considerable overlap with regards to sensory activation. LÄS MER
4. Gut Feelings - From Brain to Gut and from Lumen to Gut
Sammanfattning : Part 1: From Brain to GutThe brain is an organ with a high energy requirement. To meet this demand, the brain needs a continuous and well-regulated blood supply. In situations where the brain, or parts of the brain, does not receive sufficient blood flow injury arise. LÄS MER
5. Interactions between the brain and the immune system in pain and inflammation
Sammanfattning : Reciprocal interactions between the nervous and immune systems have gained a lot of attention in the last two decades, especially after demonstrating that cytokine immunotherapies can induce depression and after describing the inflammatory reflex. A lot of effort has been dedicated to understanding how the signals from the immune system reach the brain and vice versa, and on their role in health and disease. LÄS MER