Sökning: "passive immunity"
Visar resultat 1 - 5 av 22 avhandlingar innehållade orden passive immunity.
1. Development of the gastrointestinal tract in young mammals : Effects of enteral provocation with protease or phytohaemagglutinin in neonatal rats
Sammanfattning : The rat, as an altritial species, is born with an immature gastrointestinal tract and intestinal barrier function, which is highly absorptive to milk-borne bioactive molecules that can pass undigested and reach the general circulation of the suckling newborn. This passage occurs by the neonatal-Fc-receptor (FcRn) binding and trancytosis of immunoglobulin G in the proximal small intestine (SI) and by the highly endocytic vacuolated enterocytes non-selectively in the distal SI. LÄS MER
2. Mechanisms triggering the recruitment of mast cell progenitors to the lung and regulation of mast cell degranulation
Sammanfattning : Mast cells stem from the bone marrow and migrate via the blood as mast cell progenitors. Upon arrival in peripheral tissues, they develop into mast cells. These rare immune cells have numerous granules that contain large amounts of pro-inflammatory mediators. LÄS MER
3. Studies on bacteria resistant and susceptible to humoral immunity in insects
Sammanfattning : Insects have developed several defense mechanisms against microorganismsi The injection of live bacteria into Lepidoptera pupae induces the synthesis of several bactericidal proteins, especially the cecropins and the attacins. Important properties of an insect pathogenic bacterium are invasiveness and resistance to immunity. LÄS MER
4. Harnessing T cell immunity for the prevention and treatment of liver cancer
Sammanfattning : Hepatocellular carcinoma (HCC) accounts for more than 80% of all diagnosed cases of liver cancer which is a major cause of cancer related fatalities worldwide. With few improvements in the survival rates during the last decades, prevention of HCC is key in reducing its burden globally. LÄS MER
5. Humoral immunity during primate lentivirus infection : evaluation of B cell apoptosis and engineering of virus specific antibodies
Sammanfattning : The focus of this project was to evaluate the contribution of the humoral immunity in controlling infection with primate lentiviruses - an area which has implications both for vaccine design as well as for understanding of the pathogenesis of the disease. The first goal was to generate efficient neutralizing reagents which could be used for passive immunotherapy trials, preferably in the macaque system, and to investigate if peptide immunogens could elicit such antibodies. LÄS MER
