Sökning: "wittig"

Visar resultat 6 - 10 av 13 avhandlingar innehållade ordet wittig.

  1. 6. Novel Approaches to Phosphorus-containing Heterocycles and Cumulenes

    Författare :Anna Arkhypchuk; Sascha Ott; John D. Protasiewicz; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; phosphorus; phosphole; oxaphosphole; cumulene; phospha-Wittig-Horner reagent; molecular electronics; Chemistry; Kemi;

    Sammanfattning : Fast development in all areas of life and science over the last 50 years demands versatile, energy efficient and cheap materials with specific but easily tuneable properties which can be used for example in organic light emitting diodes (OLEDs), thin-film transistors, photovoltaic cells, etc. This thesis is devoted to the development of novel synthetic approaches to molecules with potential applications in the field of molecular electronics. LÄS MER

  3. 7. Palladium-promoted synthesis of compounds labelled with ¹¹C : Synthesis of ¹¹C-labelled prostacyclin and prostaglandin analogues

    Författare :Margareta Björkman; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; Chemistry; Kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : Palladium-promoted reactions have been employed for the synthesis of compounds labelled with 11C (t½ = 20.3 min). The precursor [11C]methyl iodide was used in palladium-promoted cross-coupling reactions with organostannanes. LÄS MER

  4. 8. Selectivity in Host-Guest Chemistry

    Författare :Gunnar Westman; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : This thesis describes host-guest complexes with the use of a biphenyl crown ether or cyclodextrin as host. Complexes between the biphenyl crown ether and salts form phenylalanine esters were studied. LÄS MER

  5. 9. Synthesis of 11C-labelled monosaccharides

    Författare :Mattias Ögren; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; Chemistry; Kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : The synthesis of some 11C-labelled (tl/2=20.3 min) monosaccharides is presented. Terminal labelled alkenes were synthesized and selectively oxidized using asymmetric dihydroxylation (AD) and palladium(II)-promoted oxidation. The labelled polyols obtained after the AD were submitted to enzymatic oxidations. LÄS MER

  7. 10. A Chemical Approach Toward the Therapeutic Optimization of Cytotoxic Bioconjugates

    Författare :Rafael Hartmann; Luke R. Odell; Fredrik Lehmann; Mats Larhed; Dario Neri; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemotherapy; antibody-drug conjugates; organic synthesis; bioorganic chemistry; synthetic method development; analytical method development; Chemistry with specialization in Bioorganic Chemistry; Kemi med inriktning mot bioorganisk kemi; Medicinal Chemistry; Läkemedelskemi; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Sammanfattning : The delivery of cytotoxicity to specific cells was recognized to be the key to the effective, chemical treatment of infectious and neoplastic diseases well over a century ago. In the context of oncology, the primary therapeutic challenge is the distinction between healthy and pathological cells despite their pronounced pheno- and genotypic similarity. LÄS MER