Sökning: "tumour stroma"

Visar resultat 6 - 10 av 34 avhandlingar innehållade orden tumour stroma.

  1. 6. Studies of Stroma Formation and Regulation in Human Pathological Conditions and in Experimental in vivo Models

    Författare :Alejandro Rodriguez; Christian Sundberg; Kristian Pietras; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fibrosis; Tumor Stroma; Myofibroblast; Pericyte; Angiogenesis; Inflammation; adenovirus; Tumour biology; Tumörbiologi; Molecular medicine; Molekylär medicin; Medical Biochemistry; Medicinsk biokemi;

    Sammanfattning : Fibrosis is a sequel of chronic inflammation and is defined as an excessive deposition of collagen that ultimately leads to organ dysfunction. To date there are no effective treatments for fibrosis. The main cell type involved in collagen deposition and organization is the myofibroblast. LÄS MER

  2. 7. Tumour stromal and demographical factors affecting the metastatic aggressiveness of small differentiated papillary thyroid cancers in Sweden

    Författare :Haytham Bayadsi; Joakim Hennings; Malin Sund; Robert Bränström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Papillary thyroid cancer; Tumour stroma; Geographic information system; Register; Surgery; kirurgi;

    Sammanfattning : Background: The incidence of papillary thyroid cancer (PTC) has been increasing over the recent decades, especially that of small papillary thyroid cancers (sPTCs) (≤ 20mm in size). sPTCs are generally classified as low risk cancers with a very favourable diagnosis, yet some of these cancers still cause locoregional and distant metastasis, recurrence and even death. LÄS MER

  3. 8. Prognostic markers in colorectal cancer : aspects of proliferation, tumour stroma and genetic changes

    Författare :Ulf Kressner; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 9. Tumour Biological Factors Characterizing Metastasizing Serotonin-producing Ileocaecal Carcinoids

    Författare :Janet Lynn Cunningham; Eva Tiensuu Janson; Kjell Öberg; Irvin M. Modlin; Uppsala universitet; []
    Nyckelord :Internal medicine; endocrine tumour; midgut carcinoid; serotonin-producing neuroendocrine carcinoma; prognosis; morphology; tachykinin; connective tissue growth factor; islet autoantigen-2; morphology; carcinoid syndrome; Invärtesmedicin;

    Sammanfattning : In this study, metastasizing serotonin-producing ileocaecal carcinoid tumours (MSPCs) were examined for biological characteristics that could be used to define clinically relevant subgroups within this patient population. Possible targets for new treatment options were also explored. LÄS MER

  5. 10. Tissue remodelling proteases as prognostic factors in colon and rectal cancer

    Författare :Marcus Langenskiöld; Göteborgs universitet; []
    Nyckelord :extracelluar matrix; survival; staging; colorectal cancer; mucosa; stroma;

    Sammanfattning : Background: Colorectal cancer is the third most common cancer in Sweden and the main treatment is surgery. The TNM classification is the principal staging tool, although insufficient in identifying all patients with poor survival. LÄS MER