Sökning: "tumour cells"

Visar resultat 31 - 35 av 523 avhandlingar innehållade orden tumour cells.

  1. 31. Molecular and epigenetic control of CNS tumour and progenitor cells

    Författare :Aileen Gracias; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Despite advances in diagnosis and treatment, CNS tumours continue to result in high mortality and morbidity. Glioblastoma mutliforme (GBM), the most common primary brain tumour, is a recurrent tumour that despite advances in treatment, continues to demonstrate a median time of survival of 14.6 months. LÄS MER

  3. 32. Extracellular Matrix and Connective Tissue Cells of the Tumor Microenvironment

    Författare :Tomas Friman; Christian Sundberg; Kristofer Rubin; Ulf Eriksson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Tumour biology; Tumörbiologi; Medical Science; Medicinsk vetenskap;

    Sammanfattning : In addition to malignant cells, solid tumors comprise supporting stromal tissue that consists of extra cellular matrix (ECM), connective tissue cells, inflammatory cells and blood vessels. The stromal compartment and the malignant cells together shape the tumor microenvironment that in turn determines tumor progression and efficacy of anti-tumor treatments. LÄS MER

  4. 33. Cancer and Therapy: A look into stemness and the tumour microenvironment

    Författare :Carmen Rodriguez; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; COMP; STRIPAK; Notch; p21; oncofetal chondroitin sulfate; therapy; tumour microenvironment;

    Sammanfattning : Therapy is the often-used treatment for cancer patients, even those that undergo resection surgery. While milestones have been surpassed throughout the decades for a number of cancer types, there are those that comprise of characteristics limiting effectiveness of treatments. LÄS MER

  5. 34. Small intestinal neuroendocrine tumours - Disease models, tumour development, and remedy

    Författare :Tobias Hofving; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroendocrine tumours; tumour models; SMAD4; 177Lu-octreotate therapy; immunotherapy;

    Sammanfattning : Small intestinal neuroendocrine tumours (SINETs) are malignant neoplasms which at the time of diagnosis often present with distant metastasis. The field of SINET research faces several challenges. LÄS MER

  7. 35. Theoretical modelling of tumour oxygenation and influences on treatment outcome

    Författare :Iuliana Toma-Dasu; Mikael Karlsson; Svensson Hans; J F Fowler; Borivoj Vojnovic; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiation sciences; Computer simulation; Electrode; Polarographic measurements; Tumour oxygenation; Hypoxia; Strålningsvetenskap; Radiation biology; Strålningsbiologi; radiofysik; radiation physics;

    Sammanfattning : One of the main problems in curing cancer resides in the different microenvironment existing in tumours compared to the normal tissues. The mechanisms of failure are different for radiotherapy and chemotherapy, but they all relate to the poor blood supply known to exist in tumours. LÄS MER