Sökning: "tumour cells"
Visar resultat 21 - 25 av 522 avhandlingar innehållade orden tumour cells.
21. Specific anti-tumour effects of 6-diazo-5-oxo-L-norleucine (DON) on carcinoid tumour cells
Sammanfattning : Glutamine is essential for cell growth. 6-diazo-5-oxo-L-norleucine (DON) is a rather old anti-tumour drug developed as a glutamine antagonist. Previous clinical trials with DON, not including carcinoid tumours, did not prove convincing. Hence the drug was not further used. LÄS MER
22. Regulation of apoptosis during treatment and resistance development in tumour cells
Sammanfattning : Induction of apoptosis is the most studied cell death process and it is a tightly regulated physiological event that enables elimination of damaged and unwanted cells. Apoptosis can be induced via activation of either the intrinsic or the extrinsic signalling pathway. LÄS MER
23. Investigations of Proneural Glioblastoma to Identify Novel Therapeutic Targets
Sammanfattning : Malignant glioma is a highly lethal and destructive disease with no proper cure. We have investigated some of the hallmarks of cancer in connection to glioma and found ways to disrupt these and prevent tumor growth. The work is done within the context of a glioma subtype distinguished by activation of PDGF signaling termed the proneural subtype. LÄS MER
24. Radioimmunotherapy in Experimental Head and Neck Squamous Cell Carcinoma : Tumour-targeting in vitro and in vivo
Sammanfattning : Radioimmunotherapy (RIT) has been shown to be a practicable way to treat head and neck squamous cell carcinoma. A specific antibody recognizes the charasteristic structure of tumour cells when loaded with cytotoxic agents (toxins, drugs, radionuclides, etc). LÄS MER
25. Transcriptome-wide analysis in cells and tissues
Sammanfattning : High-throughput sequencing has greatly influenced the amount of data produced and biological questions asked and answered. Sequencing approaches have also enabled rapid development of related technological fields such as single-cell and spatially resolved expression profiling. LÄS MER