Sökning: "tumor periphery"

Visar resultat 11 - 15 av 15 avhandlingar innehållade orden tumor periphery.

  1. 11. Validation of biomarkers and digital image analysis in breast pathology

    Författare :Gustav Stålhammar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : For women worldwide, the risk of developing breast cancer is second only to that of nonmelanoma skin cancer. Significant improvements have been made in survival over the past decades and today about 80 % of the patients survive 10 years or more after their breast cancer diagnosis. LÄS MER

  3. 12. SBRT of large tumors and tumors located near organs at risk in the thoracic cavity

    Författare :Vitali Grozman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Stereotactic Body Radiotherapy (SBRT) is a non-invasive ablative radiation therapy developed at Karolinska University Hospital in the early 90-s. Its basic principles are highly focused inhomogeneous dose load with rapid fall of in the periphery of the target, delivered in few fractions with high-doses per fraction. LÄS MER

  4. 13. T Regulatory Cells – Friends or Foes?

    Författare :Camilla Lindqvist; Angelica Loskog; Thomas Tötterman; Vivianne Malmström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Treg; T regulatory cell; FoxP3; CD25; CLL; B-cell lymphoma; Clinical immunology; Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : T regulatory cells (Tregs) have been extensively studied in patients with cancer or autoimmunity. These cells hamper the immune system’s ability to clear tumor cells in cancer patients. In autoimmune diseases, on the other hand, they are not able to restrain autoreactive immune responses. LÄS MER

  5. 14. Gene expression of selected immune regulatory molecules in neuroimmunological diseases

    Författare :Wen-Xin Huang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Multiple sclerosis (MS) is an inflammatory, demyelinating disease that is specific to the central nervous system (CNS). Myasthenia gravis (MG) is a disorder of the neuromuscular junction. Both MS and MG are usually considered autoimmune diseases but how the immune system is involved is poorly understood. LÄS MER

  7. 15. Intracranial facial nerve lesion : experimental study on neural degeneration and its treatment

    Författare :Per Mattsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The aim of this thesis was to develop an experimental model that would generate extensive motor neuronal degeneration in adult rats, and furthermore to study mechanisms causing nerve cell death and effects of putative neuroprotective compounds. The facial nerve was chosen because it is well characterized and allows evaluation of functional recovery by analyzing vibrissae movements. LÄS MER