Sökning: "tissue reactions"

Visar resultat 41 - 45 av 224 avhandlingar innehållade orden tissue reactions.

  1. 41. Markers for clinical outcome and therapy response in soft tissue sarcomas

    Författare :Jan Åhlen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Soft-tissue sarcomas (STSs) constitute a heterogeneous group of rare but aggressive tumors that originate from mesenchymal cells in almost any part of the body. Gastrointestinal stromal tumor (GIST), located in the gastrointestinal tract, is the most common type of STS. LÄS MER

  2. 42. On the role of HMGB1 and IL-1 in tissue barrier defense

    Författare :Cecilia Zetterström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The specialized epithelial surfaces of the lymphoepithelial tissue in the airways and the seminiferous epithelium of the testis are sites of host-environmental interaction at the same time as they serve important physiological functions in gas exchange and reproduction. The host response of a broken epithelial barrier requires rapid mechanisms to control the microflora and to prevent invasion of pathogens. LÄS MER

  3. 43. Tissue microbiology : an integrated approach for intravital studies of host-pathogen interactions

    Författare :Ferdinand Xiankeng Choong; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : A bacteria infection in the living host is the summation of a myriad of interactions. Reductionistic and sacrificial experiment models cannot replicate this complexity. The Tissue Microbiology approach overcomes this by allowing the live host and pathogen to control all facets of the infection model. LÄS MER

  4. 44. Reactions of Model and Anticancer Active Platinum(IV/II) Complexes - A Kinetic and Mechanistic Study

    Författare :Kelemu Lemma; Kemiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Model Pt II complexes; Anticancer active Pt IV compounds; Cisplatin; Rescue agents; L-Ascorbic acid; Thiol; Substitution; Kinetics and mechanism; Electron transfer; Inorganic chemistry; Oorganisk kemi;

    Sammanfattning : In this thesis reductions of model and anticancer active Pt(IV) complexes with thiols and ascorbic acid and substitution reactions of cisplatin and model Pt(II) complexes with S-donor nucleophiles (rescue agents) have been investigated using stopped-flow and UV/VIS spectrophotometry. Glutathione (GSH) reduction of the anticancer active Pt(IV) compounds t- and c-[PtCl4(cha)(NH3)] (cha = cyclohexylamine), t-[PtCl4(thiazole)(NH3)] and c-[PtCl4(NH3)2] at 25 oC was observed to be very fast. LÄS MER

  5. 45. Nano-porous Alumina, a Potential Bone Implant Coating

    Författare :Marjam Karlsson; Karin Caldwell; Mats Boman; Matteo Santin; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Nano-porous aluminium oxide; Biomaterial; Hard tissue implant; Surface topography; Osteoblast; Biocompatibility; Neutrophil; Inflammation; Kemi; Chemistry; Kemi;

    Sammanfattning : This thesis describes a method of growing a highly adherent nano-porous alumina coating on titanium implant materials, a design which might be useful in hard tissue replacement. Alumina layers were formed by anodisation of aluminium, which had been deposited on titanium and titanium alloys by electron beam evaporation. LÄS MER