Sökning: "thyroid autoantibodies adolescents enterovirus infection thyroid ultrasonography reference standard goiter chronic autoimmune thyroiditis levothyroxine treatment Medicin människa och djur Medicine human and vertebrates children"
Hittade 1 avhandling innehållade orden thyroid autoantibodies adolescents enterovirus infection thyroid ultrasonography reference standard goiter chronic autoimmune thyroiditis levothyroxine treatment Medicin människa och djur Medicine human and vertebrates children.
1. Aspects of chronic autoimmune thyroiditis in children and adolescents
Sammanfattning : The aims of this thesis were to 1) compare different methods for detection of antibodies against thyroglobulin (TgAb) and thyroid peroxidase (TPOAb), particulary in children with chronic autoimmune thyroditis (AIT), 2) investigate if maternal enterovirus infection is a risk factor for development of AIT in offspring, 3) ascertain the prevalence of thyroid autoantibodies in cord blood sera from children who later developed AIT, 4) develop a new reference standard for interpretation of normative thyroid volumes in Swedish children, and 5) evaluate the effect of Levothyroxine (L-thyroxine) treatment on thyroid size in children and adolescents with AIT. We found that 1) Methods based on radioimmunoassay (RIA) were more efficient in detecting both TgAb and TPOAb in children with AIT than methods based on agglutination. LÄS MER
