Sökning: "thy-1"

Hittade 3 avhandlingar innehållade ordet thy-1.

  1. 1. Human spinal cord transplantation : experimental and clinical application

    Författare :Elisabet Åkesson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The main objectives of this Thesis was to further characterize the in situ human first trimester spinal cord tissue and to evaluate the survival, integration and possible neurological effects of solid human embryonic spinal cord grafts transplanted to cavities in the spinal cord of rat and man. Human-specific neurofilament and Thy-1 positive fibers were observed already at 5 weeks of gestation in the in situ human spinal cord, the earliest stage at which donor tissue was used for intraspinal transplantation. LÄS MER

  3. 2. Identification and Characterization of Stem Cells in Preleukemia and Leukemia

    Författare :Lars Nilsson; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haematology; extracellulära vätskor; Hematologi; Philadelphia chromosome; acute lymphoblastic leukemia; polycytemia vera; 5q- syndrome; myelodysplastic syndromes; self-renewal; preleukemia; Hematopoietic stem cells; leukemic stem cells; extracellular fluids;

    Sammanfattning : Hematopoietic stem cells (HSCs) are responsible for the daily and life long production of large numbers of mature blood cells through highly regulated self-renewal and multilineage capabilities. Leukemias on the other hand, are characterized by a clonal, dysregulated, lineage skewed proliferation and impaired differentiation as the result of multiple accumulated genetic events. LÄS MER

  4. 3. Molecular mechanisms involved in the growth of human uterine leiomyomas

    Författare :Xuxia Wu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Human uterine leiomyomas; myometrium; the menstrual cycle; estrogen; progesterone; cellular proliferation; apoptosis; oncogene; growth factor; growth factor receptor.;

    Sammanfattning : Human uterine leiomyomas (fibroids) are benign neoplasms arising from uterine smooth muscle cells, and are suggested to be sex steroid dependent. The aim of this study was to investigate the molecular mechanisms by which sex steroids, mainly estrogen and progesterone, influence the growth of Ieiomyomas. LÄS MER