Sökning: "cellular proliferation"

Visar resultat 1 - 5 av 566 avhandlingar innehållade orden cellular proliferation.

  1. 1. Regulation of cellular growth and identification of stromal gene signatures in breast cancer

    Författare :Sofia Winslow; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; cellular stress; proliferation; PKCα; G3BP; PMP22; miR-34c; gene expression profiles; stroma;

    Sammanfattning : Normal tissue is tightly controlled to keep a balance between reproduction and elimination of cells. In cancer, these regulated processes are disrupted, resulting in uncontrolled cell growth. Regulation of RNA stability and turnover is important to maintain cellular homeostasis and can be controlled by various mechanisms. LÄS MER

  3. 2. Corneal cellular proliferation and wound healing

    Författare :Lisha Gan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :cornea; cell proliferation; wound healing; stem-cells; leukocytes; PCNA; hyaluronan; alkali injury; photorefractive keratectomy;

    Sammanfattning : Background: Cellular proliferation plays an important role in both physiological and pathological processes. Epithelial hyperplasia in the epithelium, excessive scar formation in retrocorneal membrane formation and neovascularization are examples of excessive proliferation of cornea cells. Lack of proliferative ability causes corneal degeneration. LÄS MER

  4. 3. Neural Stem and Progenitor Cells : Cellular Responses to Known and Novel Factors

    Författare :Jimmy Larsson; Karin Forsberg-Nilsson; Ola Hermanson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural stem cell; differentiation; proliferation; migration; PDGF; SCF; NRBP2; medulloblastoma; Biochemistry; Biokemi; Medical Biochemistry; Medicinsk biokemi;

    Sammanfattning : Neural stem cell self-renewal and differentiation are tightly regulated events during CNS development, leading to cell division into new neural stem cells or the formation of neurons and glial cells. This thesis focuses on the cellular responses induced by known and novel factors in neural stem and progenitor cells (NSPCs). LÄS MER

  5. 4. NEURAL STEM/PROGENITOR CELLS IN THE POST-ISCHEMIC ENVIRONMENT: Proliferation, Differentiation and Neuroprotection

    Författare :Jonas Faijerson; Göteborgs universitet; []
    Nyckelord :neural stem cells; neural progenitor cells; stroke; ischemia; reactive astrocytes; astrogliosis; proliferation; differentiation; neurogenesis; excitotoxicity; transfection; neuroprotection;

    Sammanfattning : Stroke is one of the leading causes of chronic disability and death in the Western world. Today, no treatment can repair the cellular loss associated with an ischemic lesion. LÄS MER

  7. 5. Cellular Effects of Cystatins

    Författare :Samar Hunaiti; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cystatin C; Cystatin D; Galectin-1; Puncta assay; HoloMonitor; Cancer cells; Apoptosis; Cathepsin C;

    Sammanfattning : The exact cellular functions of cystatins are still unknown, and the molecular mechanism leading to their internalization into cells is not yet fully understood. Commonly the cystatins are known to inhibit human lysosomal cysteine proteases (cysteine cathepsins) and it is supposed that this is their primary physiological role. LÄS MER