Sökning: "telomerase hTERT"

Visar resultat 21 - 25 av 28 avhandlingar innehållade orden telomerase hTERT.

  1. 21. Novel mechanisms in depression: focus on telomere biology and epigenetic regulation

    Författare :Yabin Wei; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Telomere length;

    Sammanfattning : Depression is a complex disorder with an average lifetime prevalence from 11.1% to 14.6%. It causes serious disability and is a significant public health problem worldwide. LÄS MER

  3. 22. Studies on the mechanisms of carcinogenesis and cancer cell death

    Författare :Qiao Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Gastric cancer is the second most common cause of cancer-related mortality in the world. The mechanisms of gastric carcinogenesis are not fully elucidated. LÄS MER

  4. 23. p16INK4A and p15INK4B in senescence, immortalization and cancer : gene transfer by adenovirus vectors

    Författare :Jonas Fuxe; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The astrocytic gliomas are the most common form of brain tumors in humans. The malignant progression from low grade (astrocytoma, grade II) to high-grade (glioblastoma multiforme, grade, IV) astrocytomas is well documented and is accompanied by an increasing number of genetic aberrations. LÄS MER

  5. 24. Expression and activity of Myc network proteins during cell cycle progression and differentiation

    Författare :Nikita Popov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Transcription factors of Myc network are the key regulators of cell proliferation, cell death and differentiation. Identified as a transforming oncogene, myc is the driving force of a variety of human cancers, and inactivation of myc in tumors can cause their rapid regression. LÄS MER

  7. 25. Pheochromocytoma and abdominal paraganglioma : clinical and genetic aspects

    Författare :Elisabet Edström Elder; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Pheochromocytomas; abdominal paragangliomas; RET; MEN 2A; tumour development; chromosome 1; comparative genomic hybridisation; in situ hybridization; loss of heterozygosity.;

    Sammanfattning : Pheochromocytomas and abdominal paragangliomas are rare catecholamine producing tumours arising from sympathoadrenal paraganglia located within and outside of the adrenal medulla, respectively. The great majority of tumours are benign and cured by surgery. LÄS MER