Sökning: "surface marker"

Visar resultat 16 - 20 av 136 avhandlingar innehållade orden surface marker.

1. 16. Electrical remodeling in arial fibrillation - assessment using surface electrocardiograms, prognostic implications and potential reversal

   Författare :Andreas Bollmann; Kardiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atrial fibrillation; electrocardiography; stroke; biomarkers;

   Sammanfattning : The fibrillatory rate of the surface ECG during atrial fibrillation (AF) has been suggested for quantification of the individual atrial remodeling, to monitor interventions and to predict the response to different therapies. In this dissertation, the relation between fibrillatory rate of the surface ECG and (1) clinical and echocardiographic variables, (2) the outcome of cardioversion, (3) circulating markers of inflammation and hemostasis, (4) the risk of left atrial thrombus formation, (5) the risk of stroke, and (6) the effects of candesartan on the fibrillatory rate were investigated in human persistent atrial fibrillation (AF). LÄS MER

3. 17. Expression of Tissue Antigens in Human Pluripotent Stem Cells and Alterations During Differentiation : Potential application in regenerative medicine for treatment of terminal cell and organ failure

   Författare :Karin Säljö; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pluripotent stem cells; Differentiation; Histo-blood group antigens; HLA; Tissue antigens; Sialyl-lactotetra; Cell surface antigens; Transplantation; Regenerative medicine;

   Sammanfattning : The major limiting factor in the treatment of patients with end-stage organ failure is the insufficient number of human organs available for transplantation. An unlimited access to human cells, tissues and organs would also open up possibilities to treat several chronic diseases, such as diabetes, neurological and cardiovascular diseases, affecting millions of patients worldwide. LÄS MER

4. 18. Studies on glycosphingolipids in regenerative medicine

   Författare :Angela Barone; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glycosphingolipids; human embryonic stem cells; Cell surface markers; porcine heart valves; xenotransplantation; regenerative medicinr;

   Sammanfattning : Regenerative medicine, including stem cell based therapies and xenotransplantation, is a new and developing field that aims to restore normal function in end stage cell/organ failure. However, in therapeutic settings involving transfer of cells with a different genetic background, these cells will expose the recipient to non-self cell surface antigenic determinants that may evoke an immune response and subsequent graft damage. LÄS MER

5. 19. The osteogenic potential of human mesenchymal stem cells: Novel markers and key factors for differentiation

   Författare :Cecilia Granéli; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenchymal stem cells; Mesenchymal stromal cells; Osteogenic differentiation; Adipogenic differentiation; Bone regeneration; Inflammation; Monocytes; Infection; Bacterial membrane vesicles; Compromised bone healing; Cell surface proteins; CD-markers; Osseointegration; Regenerative medicine;

   Sammanfattning : Mesenchymal stem cells are multipotent stem cells with ability to differentiate into cells of the connective tissue lineage, such as adipocytes, osteoblasts and chondrocytes, both in vitro and in vivo. The main objective of the present thesis was to study different aspects of the osteogenic potential of MSCs. LÄS MER

7. 20. Carotid artery disease : plaque features and vulnerability

   Författare :Fisnik Jashari; Michael Henein; Per Wester; Christine Kremer; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Carotid atherosclerosis; ultrasound; plaque features; echogenicity; calcification; surface plaque irregularities; subclinical atherosclerosis; cerebrovascular symptoms; Cardiology; kardiologi; cardiovascular disease; hjärt- och kärlforskning;

   Sammanfattning : Background: Atherosclerosis is an important cause of stroke. Ultrasound offers the convenience of real-time and detailed assessment of carotid plaque features as well as arterial wall thickening and composition. LÄS MER