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Visar resultat 1 - 5 av 21 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Structural studies of three cell signaling proteins : crystal structures of EphB1, PTPA, and YegS

   Författare :Amin Bakali; Pär Nordlund; Wenqing Xu; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein production; structural genomics; cell signaling; Biochemistry; Biokemi;

   Sammanfattning : Kinases and phosphatases are key regulatory proteins in the cell. The disruption of their activities leads ultimately to the abolishment of the homeostasis of the cell, and is frequently correlated with cancer. EphB1 is a member of the largest family of receptor tyrosine kinases. It is associated with neurogenesis, angiogenesis, and cancer. LÄS MER

3. 2. On Ground and Structural Vibrations Related to Railway Traffic

   Författare :Johan O. Jonsson; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; wave propagation; wave field excitation; soil structure interaction; structural vibration; ground vibration; traffic vibration;

   Sammanfattning : The continuous development and integration of railway infrastructure, especially within urban areas, can cause ground and building vibrations to reach levels that bring discomfort to people. The growing risk of damage to buildings located in areas prone to ground vibration should not be underestimated. LÄS MER

4. 3. Structural Insights into Botulinum Neurotoxins and the ALFA-tag System : Structural and Functional Studies of Proteins Related to the Botulinum Neurotoxins and Design of a Novel Epitope Tag

   Författare :Markel Martínez-Carranza; Pål Stenmark; Thomas Binz; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; botulinum neurotoxin; Biochemistry; biokemi;

   Sammanfattning : This thesis is divided into two sections; the first part describes our work in the field of botulinum neurotoxins (presented in papers I, II, III, and manuscript IV) and the second part summarizes our work involving the design of a new biochemical tool (presented in paper V).Botulinum neurotoxins (BoNTs) produced by the anaerobic bacterium Clostridium botulinum are the most poisonous substances known to date. LÄS MER

5. 4. Essays in economics : The impact of changes on the labor market induced by structural change, the adoption of a new computer-based technology and economic slowdowns on family formation, family fertility outcomes and new careers

   Författare :Tamara Thornquist; Peter Skogman Thoursie; Jonas Vlachos; Hans Grönqvist; Stockholms universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Labor market; structural change; polarization of earnings; computer-based technology; economic slowdowns; family formation; family fertility outcomes; careers; college graduates; Economics; nationalekonomi;

   Sammanfattning : Childlessness, Number of Children and The Labor Market at the Time of a New Technology, the US 1980-2018The adoption of a new computer-based technology in the US in the late 1970s resulted in broad changes on the labor market that can be described by two major phenomena - job polarization and a shift in the relative returns to skill. A well established theoretical and empirical literature shows that commuting zones with a historically greater specialization in routine task intensive occupations adopted the new computer-based technology faster and subsequently saw greater changes on the local labor markets. LÄS MER

7. 5. Power System Damping - Structural Aspects of Controlling Active Power

   Författare :Olof Samuelsson; Industriell elektroteknik och automation; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Electronics and Electrical technology; controller interaction; mode controllability; mode observability; mechanical equivalent; linear differential-algebraic equations; modal analysis; active power; power system damping; electro-mechanical oscillations; Elektronik och elektroteknik; Automation; robotics; control engineering; Automatiska system; robotteknik; reglerteknik;

   Sammanfattning : Environmental and economical aspects make it difficult to build new power lines and to reinforce existing ones. The continued growth in demand for electric power must therefore to a great extent be met by increased loading of available lines. LÄS MER