Sökning: "receptor characterization"

Visar resultat 36 - 40 av 263 avhandlingar innehållade orden receptor characterization.

  1. 36. Characterization and targeting of leukemia propagating cells

    Författare :Stina Virding Culleton; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Patients with hematopoietic malignancies have a large, unmet medical need. Allogeneic hematopoietic stem cell transplantation remains the only curative option, but many patients are not eligible for such treatment. LÄS MER

  3. 37. Characterization of cholorplast protein import in Arabidopsis thaliana with emphasis on Toc64 and Tic55

    Författare :Patrik Boij; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; chloroplast import; non-essential receptor; Toc64; redox control; Tic55; DEPC; substrate dependent pathway; PTC52; proteomics;

    Sammanfattning : Although the chloroplast possesses a genome of its own most genes have been transferred during the evolution to the nucleus to acquire more transcriptional control, and couple the activities of the wh... merole cell to events at the chloroplast. LÄS MER

  4. 38. Dopamine D2 and D3 receptors. Studies on transduction mechanisms and on the role of a D3 gene polymorphism

    Författare :Monika Hellstrand; Göteborgs universitet; []
    Nyckelord :dopamine; dopamine D2 receptor; dopamine D3 receptor; transduction; CHO cells; partial agonism; inverse agonism; arachidonic acid; prostaglandin E2; cAMP; haloperidol; -3-PPP; PNU-99194A; polymorphism; personality;

    Sammanfattning : The neurotransmitter dopamine has been implicated in the pathophysiology of, e.g., Parkinson s disease and schizophrenia, and dopamine receptor-active compounds are commonly employed therapeutically in these and other disorders. LÄS MER

  5. 39. Characterization of peroxisome proliferator-activated receptor alpha (PPARa) regulated acyl-CoA thioesterases involved in lipid metabolism

    Författare :Mary C Hunt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Acyl-CoA thioesterase; acyl-CoA; peroxisome proliferator-activated receptor alpha; coenzyme A; bile acid metabolism; lipid metabolism.;

    Sammanfattning : The peroxisome proliferator-activated receptor alpha (PPARalpha) is a key nuclear receptor in the control of lipid metabolism. Target genes for PPARalpha include many enzymes involved in the oxidation of fatty acids in mitochondria and peroxisomes. LÄS MER

  7. 40. Cloning and characterization of neuropeptide Y receptors of the Y1 subfamily in mammals and fish

    Författare :Paula Starbäck; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; G-protein; neuropeptide Y; panacreatic polypeptide; neuropeptide Y receptor; ortholog; zebrafish; guinea pig; pseudogene; evolution; Neurovetenskap; Neurology; Neurologi; Neurology; neurologi;

    Sammanfattning : Neuropeptide Y (NPY) is an abundant neurotransmitter in the nervous system and forms a family of evolutionarily related peptides together with peptide YY (PYY), pancreatic polypeptide (PP) and polypeptide Y (PY). These peptides are ligands to a family of receptors that mediate a wide range of physiological effects including stimulation of appetite. LÄS MER