Sökning: "protein sorting"

Visar resultat 16 - 20 av 99 avhandlingar innehållade orden protein sorting.

  1. 16. On the Biosynthesis and Processing of Cathepsin G, Leukocyte Elastase, and Azurocidin ­ neutrophil granule members of a hematopoietic serine protease superfamily

    Författare :Anders Lindmark; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Haematology; sorting; Activation; propeptide; Hematologi; extracellulära vätskor;

    Sammanfattning : The serine proteases cathepsin G, leukocyte elastase, proteinase 3, and the inactive protease homologue azurocidin, stored in the azurophil granules of neutrophils, belong to a hematopoietic serine protease superfamily with members in mature effector cells of bone marrow origin. Promonocytic U-937 cells were used for studying the biosynthesis of cathepsin G and leukocyte elastase by biosynthetic radiolabelling. LÄS MER

  3. 17. Reciprocal regulation of endocytosis and signaling in Drosophila epithelial development and aberrant growth

    Författare :Dan Liu; Christos Samakovlis; Vasilios Tsarouhas; Héctor Herranz; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; endocytosis; protein sorting; RTK signaling; airway maturation; tumor-suppressive cell competition; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Endocytosis and subsequent endosomal sorting of plasma membrane proteins and nutrients are essential for cellular homeostasis. Previous work has uncovered several different internalization mechanisms, endosomal sorting routes and aspects of their regulation. LÄS MER

  4. 18. Analysis of Binding Events and Diffusion in Living Cells

    Författare :Markus Elsner; Göteborgs universitet; []
    Nyckelord :COPI; Golgi; Diffusion; Glycosyltransferases; Sorting; Molecular; Crowding;

    Sammanfattning : It is well known that diffusion is the main mode of transport in living cells, but the consequences of diffusion in a complex cellular environment are not generally appreciated. In this thesis, we have investigated several aspects of how diffusion properties influence the observability of cellular binding kinetics and how they can be used to obtain information about the environment of proteins and other molecules. LÄS MER

  5. 19. Intracellular sorting of an integral membrane protein from the nuclear pore complex

    Författare :Henrik Söderqvist; Howard J Worman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Sammanfattning : .... LÄS MER

  7. 20. Studies on cell wall-attached proteins of Streptococcus pyogenes

    Författare :Magnus Rasmussen; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insertion sequence; phase variation; collagen-like; alpha2-macroglobulin; pattern; virulence; surface protein; Stretococcus pyogenes; cell wall-attached protein; Clinical biology; Klinisk biologi;

    Sammanfattning : Cell wall-attached proteins (CWPs) are important for the virulence of Gram-positive bacteria, but are also targets for the host immune system. CWPs have a conserved COOH-terminal region, responsible for cell wall-sorting. A pattern based on this conserved region was developed. LÄS MER