Sökning: "predictions in tissue"

Visar resultat 11 - 15 av 41 avhandlingar innehållade orden predictions in tissue.

  1. 11. The Role of FCGBP in Mucus - Structure, Processing and Function

    Författare :Erik Ehrencrona; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mucus; FCGBP; IgG; IBD; COPD; Mucins; Disulphide; GDPH;

    Sammanfattning : In this thesis, a bottom-up approach was used to study the IgG Fc-binding protein (FCGBP), which next to the MUC2 mucin is the second main component of secreted mucus in small intestine and colon. FCGBP is also found in airways during inflammatory conditions with static mucus. LÄS MER

  3. 12. Mathematical modeling of fluid and solute transport in peritoneal dialysis

    Författare :Jacek Waniewski; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :diffusion; convective transport; perfusion; lymphatic absorption; ultrafiltration; osmosis; continuous ambulatory peritoneal dialysis;

    Sammanfattning : Optimization of peritoneal dialysis schedule and dialysis fluid composition needs, among others, methods for quantitative assessment of fluid and solute transport. Furthermore, an integrative quantitative description of physiological processes within the tissue, which contribute to the net transfer of fluid and solutes, is necessary for interpretation of the data and for predictions of the outcome of possible intervention into the peritoneal transport system. LÄS MER

  4. 13. Post-translational modifications of myelin oligodendrocyte glycoprotein in CNS autoimmunity

    Författare :Andreas Warnecke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Autoimmunity towards components of the central nervous system (CNS) is a driving factor of nerve demyelination in Multiple Sclerosis (MS). The etiology of autoimmunity in MS pathogenesis remains elusive, but a combination of genetic predisposition and environmental triggers is theorized to initiate this complex disease. LÄS MER

  5. 14. Monoglyceride Lipase and Hormone-Sensitive Lipase - Molecular and structural aspects

    Författare :Marie Karlsson; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; genomic organisation; baculovirus-insect cells; catalytic triad; alfa beta hydrolase fold; tissue distribution; cDNA sequence; lipolysis; adipocyte; monoglyceride lipase; hormone-sensitive lipase; chromosomal localisation; Clinical biology; Klinisk biologi;

    Sammanfattning : Triglycerides in the adipocyte are hydrolysed by means of three consecutive reactions through the combined action of two lipases: hormone-sensitive lipase (HSL) and monoglyceride lipase (MGL). HSL catalyses the first and rate-limiting step, i.e. LÄS MER

  7. 15. Computational modeling of mechanobiology in intact and healing rat Achilles tendon

    Författare :Thomas Notermans; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Collagen; Finite element model; Mechano-regulation; Mechanical Properties; Strain; Oxygen; Viscoelasticity;

    Sammanfattning : Tendons fulfill an important musculoskeletal function by enabling energy-efficient force transmission between muscles and bones. The tendon is a collagen-rich connective tissue that adapts to mechanical loading through mechanobiological processes. LÄS MER