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Visar resultat 21 - 24 av 24 avhandlingar som matchar ovanstående sökkriterier.

  1. 21. Decellularized liver extracellular matrix as a 3D scaffold for bioengineering applications

    Författare :Vamakshi Khati; Aman Russom; Håkan Jönsson; Giulia Gaudenzi; Ana Teixeira; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; liver decellularization; decellularized liver matrix bioink; bioprinting; sacrificial scaffold; viscoelasticity; bioengineering; tumor modeling; stem cell differentiation; bioreactor; Biotechnology; Bioteknologi;

    Sammanfattning : The increasing global burden of end-stage liver disease has increased the need for liver transplantation, the definitive cure. However, there is a huge discrepancy between the number of available organ donors and the number of patients waiting for transplantation, resulting in the deaths of a significant number of patients on the waiting list as only 10% of the global need for transplantation is met. LÄS MER

  3. 22. Pharmaceutical insights into improving oligonucleotide delivery and efficacy

    Författare :Osama Saher; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The power of gene therapy lies in their capacity to target a disease on a genetic level. Nucleic acid containing therapeutics can be utilized to treat, diagnose or prevent a possible disease or condition. However, the successful delivery of such molecules constitutes a major limitation. LÄS MER

  4. 23. Removal of endocrine-disrupting compounds from wastewater using molecular imprinting

    Författare :Mathieu Le Noir; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; molecular imprinting; Endocrine-disrupting compounds; wastewater; macroporous gel; trace contaminants;

    Sammanfattning : Endocrine-disrupting compounds (EDCs) such as hormones and certain pharmaceuticals (i.e. birth control pills, oestrogen replacement products and other steroids) can interfere with the regulatory systems of humans and wildlife. Many of these compounds are excreted by humans and released with sewage. LÄS MER

  5. 24. Exploring Polymer-Shelled Microbubbles: Detection Modeling and Application

    Författare :Hongjian Chen; Dmitry Grishenkov; Birgitta Janerot-Sjöberg; Tomas Jansson; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ultrasound contrast agent; polymer-shelled microbubble; ultrasound imaging; contrast pulse sequence; microbubble model; hydrodynamic cavitation; Technology and Health; Teknik och hälsa;

    Sammanfattning : Ultrasound imaging (US) is widely used in clinical practice. Given the low cost and easy access to the ultrasound machine, US has a great potential to improve the health care condition for the majority of the population in the world. The US could be significantly improved by injecting ultrasound contrast agents to opacify the bloodstream. LÄS MER