Sökning: "peroxisome proliferator-activated receptor alpha"

Visar resultat 6 - 9 av 9 avhandlingar innehållade orden peroxisome proliferator-activated receptor alpha.

  1. 6. On the regulation and effects of chronic inflammation in inflammatory bowel disease

    Författare :Olof Grip; Gastroenterologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastroenterologi; statins; monocytes; eosinophils; dysplasia; thrombosis; ulcerative colitis; Crohn s disease; inflammation; inflammatory bowel disease; Gastro-enterology;

    Sammanfattning : Inflammatory bowel disease is thought to result from the inappropriate and ongoing activation of the mucosal immune system driven by the presence of normal luminal flora. In this process monocytes/macrophages contribute to and maintain chronic inflammation by being both regulatory and effector cells. LÄS MER

  3. 7. Novel radiation targets in the endothelium and heart muscle

    Författare :Venkata Ramesh Yentrapalli; Siamak Haghdoost; William F. Morgan; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ionizing radiation; Endothelial cells; Senescence; Cardiovascular disease; Proteomics; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Worldwide, people are being exposed to natural and man-made sources of radiation. Epidemiological studies have shown an increased risk of vascular diseases in populations that have been exposed to ionizing radiation. Vascular endothelium is implicated as one of the targets for radiation leading to the development of cardiovascular diseases. LÄS MER

  4. 8. Growth hormone and PPARalpha in the regulation of genes involved in hepatic lipid metabolism

    Författare :Caroline Améen; Göteborgs universitet; []
    Nyckelord :Growth hormone; insulin; SREBP-1; lipogenic enzymes; microsomal triglyceride transfer protein; PPARalpha; LXRalpha; triglycerides; liver;

    Sammanfattning : Growth hormone (GH) plays a key role in the regulation of lipid and lipoprotein metabolism. Its sexually dimorphic secretory pattern regulates many sex-differentiated functions in the liver, such as triglyceride synthesis and VLDL secretion. LÄS MER

  5. 9. Persistent environmental pollutants and risk of cardiovascular disease

    Författare :Tessa Schillemans; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Persistent chemicals emitted in the environment can have a considerable impact on ecosystems and human health, now and in the future. One notorious group of persistent organic pollutants (POPs) is the per- and polyfluoroalkyl substances (PFAS). LÄS MER