Sökning: "optimality theory"

Visar resultat 1 - 5 av 50 avhandlingar innehållade orden optimality theory.

  1. 1. Optimisation of Clinical Trials using Bayesian Decision Theory

    Detta är en avhandling från Gothenburg : Chalmers University of Technology

    Författare :Sebastian Jobjörnsson; Göteborgs universitet.; Gothenburg University.; [2016]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; decision theory; drug regulation; pharmaceutical R D; Bayesian statistics; subgroup analysis; clinical trials; health economics; multiple testing; health economics; subgroup analysis; multiple testing; drug regulation; clinical trials; Bayesian statistics; pharmaceutical R D;

    Sammanfattning : A decision maker confronted with the task of designing a clinical trial has to consider a multitude of aspects. Large trials lead to more evidence,which in turn makes it less likely that harmful decisions are taken when deciding on future treatments for patients. LÄS MER

  2. 2. Optimality conditions for synthetic estimators

    Detta är en avhandling från Göteborg : Chalmers University of Technology

    Författare :Mats Wiklund; Göteborgs universitet.; Gothenburg University.; [1991]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; sunthetic; post stratified and composite estimator and small area statistics; post stratified and composite estimator and small area statistics;

    Sammanfattning : .... LÄS MER

  3. 3. Multivariate Aspects of Phylogenetic Comparative Methods

    Detta är en avhandling från Göteborg : University of Gothenburg

    Författare :Krzysztof Bartoszek; Göteborgs universitet.; Gothenburg University.; [2011]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; General Linear Model; Ornstein-Uhlenbeck process; Multivariate phylogenetic comparative method; Evolutionary model; Adaptation; Optimality; Measurement error; Regression; Adaptation; Major-axis regression; Reduced major-axis regression; Structural equation; Allometry; Phylogenetic inertia; Allometry; Measurement error; Structural equation; Multivariate phylogenetic comparative method; Ornstein-Uhlenbeck process; Regression; Optimality; Adaptation; Evolutionary model; Phylogenetic inertia; Adaptation; Reduced major-axis regression; Major-axis regression;

    Sammanfattning : his thesis concerns multivariate phylogenetic comparative methods. We investigate two aspects of them. The first is the bias caused by measurement error in regression studies of comparative data. We calculate the formula for the bias and show how to correct for it. LÄS MER

  4. 4. Optimal Design and Inference for Correlated Bernoulli Variables using a Simplified Cox Model

    Detta är en avhandling från Stockholm : Statistiska institutionen

    Författare :Daniel Bruce; Hans Nyquist; Werner G. Müller; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cox binary model; correlated binary data; log-odds ratio; D-optimality; E-optimality; power maximization; efficiency; SOCIAL SCIENCES Statistics; computer and systems science Statistics; SAMHÄLLSVETENSKAP Statistik; data- och systemvetenskap Statistik; statistik; Statistics;

    Sammanfattning : This thesis proposes a simplification of the model for dependent Bernoulli variables presented in Cox and Snell (1989). The simplified model, referred to as the simplified Cox model, is developed for identically distributed and dependent Bernoulli variables. LÄS MER

  5. 5. Optimal Design of Experiments for the Quadratic Logistic Model

    Detta är en avhandling från Stockholm : Department of Statistics, Stockholm University

    Författare :Ellinor Fackle Fornius; Hans Nyquist; Christos Kitsos; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Logistic regression; D-optimality; c-optimality; Canonical design space; Maximum likelihood estimation; Sequential design; Stochastic approximation; SOCIAL SCIENCES Statistics; computer and systems science Statistics; SAMHÄLLSVETENSKAP Statistik; data- och systemvetenskap Statistik; statistik; Statistics;

    Sammanfattning : Optimal design of experiments for binary data is the topic of this thesis. A particular logistic model including a quadratic term in the linear predictor is considered. Determining an optimal design for this model is complicated by the fact that the optimal design is dependent on the unknown true parameters. LÄS MER