Sökning: "MVB pathway"
Hittade 5 avhandlingar innehållade orden MVB pathway.
1. Cellular remodeling in response to nutrient exhaustion : From membrane contact sites to autophagy
Sammanfattning : Adaptation to fluctuating environments is critical for cellular fitness and survival. Cells need to sense changes in their surroundings and quickly adjust cellular homeostasis and metabolism accordingly. LÄS MER
2. The release of histone proteins from cells via extracellular vesicles
Sammanfattning : Histones are chromatin-associated proteins localized to the nucleus. However, extracellular histones are present in biofluids from healthy individuals and become elevated under disease conditions, such as neurodegeneration and cancer. LÄS MER
3. Systems Biology of Recombinant Protein Production by Fungi
Sammanfattning : Systems biology has emerged as a highly potent tool for studying biological processes over the last decades. However, its application to complex metabolic processes such as protein secretion is still at the infant stage. LÄS MER
4. Functional Characterization of the Yeast Tumour Suppressor Homologue Sro7p
Sammanfattning : Correct targeting of newly synthesized proteins to appropriate domains of the cell membrane is crucial to cellular architecture, polarity and function, making it no surprise that many proteins of the secretory machinery are conserved throughout evolution. This work presents a functional characterisation of the Saccharomyces cerevisiae cell polarity protein and tumour suppressor homologue, Sro7p. LÄS MER
5. Immunomodulation during human pregnancy : placental exosomes as vehicles of immune suppression
Sammanfattning : The mammalian pregnancy comprises a challenge to the maternal immune system since the fetus is semi-allogeneic and could thus be rejected. Pregnancy success is associated with the placenta that is not only essential for oxygen supply, nourishment and pregnancy hormones but also plays a role in the protection of the fetus against maternal immunologic attack. LÄS MER