Sökning: "nucleoside"

Visar resultat 11 - 15 av 151 avhandlingar innehållade ordet nucleoside.

  1. 11. Nucleoside analog toxicity and nucleoside kinase deficiency : effects on mitochondrial DNA

    Författare :Mia Bjerke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Nucleoside analogs are modified nucleosides used in treatment of cancer and viral infections. They are dependent on intracellular phosphorylation to be pharmacologically active. Deoxyribonucleoside kinases catalyze the rate-limiting step in the phosphorylation of many clinically used nucleoside analogs. LÄS MER

  3. 12. Function of wobble nucleoside modifications in tRNAs of Salmonella enterica Serovar Typhimurium

    Författare :Peng Chen; Glenn R. Björk; Paul Agris; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; tRNA; wobble nucleoside; frameshifting; translation; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Transfer RNA from all organisms has modified nucleosides and position 34 (the wobble position) is one of the most extensively modified positions. Some wobble nucleoside modifications restrict codon choice (e.g. 5-methylaminomethyl-2-thiouridine, mnm5s2U) while some extend the decoding capacity (e. LÄS MER

  4. 13. Nucleoside H-phosphonates and H-phosphonothioates : some chemical and stereochemical studies

    Författare :Mats Thelin; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Phosphonic acid's reaction towards sterically hindered acyl chlorides has been investigated. A new synthetic method for the synthesis of nucleoside Hphosphonate monoesters has been developed. Furthermore, a method for the synthesis of nucleoside H-phosphonothioate monoesters has also been developed. LÄS MER

  5. 14. Some recent developments in nucleoside chemistry

    Författare :Nafizal Hossain; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  7. 15. Studies on nucleoside and nucleotide chemistry

    Författare :Tanmaya Pathak; Ágnes Nyilas; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER