Sökning: "noise trauma"

Visar resultat 6 - 10 av 14 avhandlingar innehållade orden noise trauma.

  1. 6. Physiological aspects of cochlear excitation and neurotransmitter release

    Författare :Wanje Jäger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cochlea; cochlear microphonics; summating potential; vibratory response; tetracaine; aspartate; glutarnate; neurotransmitter; noise; hearing loss;

    Sammanfattning : Using an in vitro model of the guinea pig, the temporal bone preparation, cochlear physiology was studied. By perfusion of the scala tympani with oxygenated culture medium, the responses of the hearing organ to sound stimuli were maintained over several hours and the functional state was followed by monitoring the electrophysiological parameters cochlear microphonics (CM) and summating potential (SP). LÄS MER

  3. 7. Circadian rhythms in the auditory system

    Författare :Vasiliki Basinou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Circadian clocks have been found in numerous cell types and tissues of the body, allowing organisms to coordinate their daily biological functions. They generate cycles of behavioral and physiological processes with a period length of ~24h, which are synchronized to the rotation of the Earth and the subsequent daily changes in illumination, temperature and humidity. LÄS MER

  4. 8. Altering the fetal programming of the HPA axis and the consequences in the adult auditory system

    Författare :Amzad Hossain; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prenatal glueocorticoid (GC) has been associated with a variety of alterations in the adult offspring. Hypothalamo-Pituitary-Adrenal (HPA) axis, which is the key regulator for almost all kind of neuroendocine function and behavior, is highly susceptible to prenatal exposure to excess GC during development. LÄS MER

  5. 9. Determinants of hearing impairment in Swedish hunters : an e-epidemiological approach

    Författare :Louise Honeth; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: 290 236 persons bought a hunting license in Sweden 2014/15. Hunters are spread all over the country and come from all socioeconomic groups. Recreational fiearms can produce peak noise levels between 156-164 decibel sound pressure levels (dB SPL). LÄS MER

  7. 10. The Round Window Membrane - Gateway to the Cochlea : A Morphological and Electrophysiological study

    Författare :Leif Nordang; Sten Hellström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Otorhinolaryngology; round window membrane; pseudomonas exotoxin; auditory brainstem response; hearing loss; endolymphatic sac; inner ear immunology; glutamate; nitric oxide inhibitor; glucocorticoid.; Otorhinolaryngologi; Otorhinolaryngology; Otorhinolaryngologi; Oto-Rhino-Laryngology; oto-rhino-laryngologi;

    Sammanfattning : Topical treatment of several inner ear diseases through the round window membrane (RWM) might be feasible in the near future. Bacteria toxins, ototoxic drugs and noise trauma seem to harm the inner ear by a common pathway which involves, excessive outflow of the afferent neurotransmitter glutamate and formation of nitric oxide (NO), which can severely damage cells/nerve endings and lead to cell death. LÄS MER