Sökning: "nitric oxide inhibitor"

Visar resultat 1 - 5 av 105 avhandlingar innehållade orden nitric oxide inhibitor.

1. 1. Inhaled Nitric Oxide Therapy : Non-response and Rebound Response

   Författare :Luni Chen; Eddie Weitzberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology and intensive care; nitric oxide inhalation; rebound response; non-response; endothelin-1; COX inhibitor; prostaglandin; ARDS; endotoxin; oleic acid; Anestesiologi och intensivvård; Anaesthetics and intensive care; Anestesiologi och intensivvård; Clinical Physiology; klinisk fysiologi;

   Sammanfattning : Therapeutic inhaled nitric oxide (INO) has proved beneficial in patients with pulmonary hypertension. However, around 30-40% of the patients are non-responders to this therapy, and a life-threatening rebound response may occur during attempts to withdraw INO. LÄS MER

3. 2. Nitric oxide production by the intestinal mucosa during hypoperfusion

   Författare :Johan Snygg; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nitric oxide; nitric oxide synthase; intestinal epithelium; hemorrhagic shock; cardiac tamponade; septic shock; lower body negative pressure; splanchnic circulation; substrate; laser Doppler;

   Sammanfattning : The present thesis is based on the concept that gastrointestinal blood hypoperfusion is a common phenomenon associated with critical illness. Furthermore, the development of the multiple organ dysfunction syndrome (MODS) is proposed to be initiated by gastrointestinal mucosal barrier dysfunction, allowing intestinal luminal contents to penetrate into the tissue and activate a systemic inflammatory response. LÄS MER

4. 3. Macula Densa Derived Nitric Oxide and Kidney Function

   Författare :Anna Ollerstam; Pontus Persson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Nitric oxide; rats; kidney; macula densa cells; tubuloglomerular feedback; renin; angiotensin II; blood pressure; hypertension; renal blood flow; neuronal nirtic oxide synthase; Cellbiologi; Cell biology; Cellbiologi; Physiology; fysiologi;

   Sammanfattning : The kidney is the major organ regulating the extracellular fluid volume and thereby the arterial blood pressure. The neuronal isoform of nitric oxide synthase (nNOS) in the kidney is predominantly located in the macula densa cells. LÄS MER

5. 4. Pulmonary Hypertension and the Nitric Oxide System

   Författare :Dan Henrohn; Gerhard Wikström; Ulla Lindqvist; John Pernow; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pulmonary hypertension; nitric oxide; ADMA; arginine; nitrate; nitrite; vardenafil; beetroot juice; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Pulmonary hypertension (PH) is a pathophysiological state associated with several medical conditions, leading to progressive rise in pulmonary vascular resistance (PVR) and right ventricular failure. The clinical PH classification encompasses five main World Health Organization (WHO) groups; pulmonary arterial hypertension (PAH), PH due to left heart disease, PH due to lung diseases and/or hypoxia, chronic thromboembolic PH, and PH with unclear multifactorial mechanisms. LÄS MER

7. 5. Nitric Oxide Regulation during Anti-tumor Immunotherapy

   Författare :Wiaam Badn; Neurokirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunologi; serology; Immunology; Medicin människa och djur ; immunotherapy; Medicine human and vertebrates ; immunosuppression; PGE2; Nitric oxide; serologi;

   Sammanfattning : During tumor progression a strong immunosuppression is developed and is believed to be the major reason why immunotherapy fails. This suppression is induced in response to factors produced from tumor cells, but can also be induced after immunotherapy. LÄS MER