Sökning: "mouse myocardium"

Visar resultat 11 - 13 av 13 avhandlingar innehållade orden mouse myocardium.

  1. 11. Myocardial metabolism in experimental infarction and heart failure

    Författare :Truls Råmunddal; Göteborgs universitet; []
    Nyckelord :Myocardial metabolism; Heart failure; Myocardial infarction; Lipotoxic heart disease; Apolipoprotein B; Arrhythmias; Cardiac reserve; Creatine metabolism;

    Sammanfattning : Abstract The heart is an organ heavily dependent on exogenous lipids for the oxidative production of adenosine-triphosphate (ATP) and therefore maintenance of normal cellular energy homeostasis. However, high energy flux organs such as the heart must closely match lipid import and utilization or otherwise lipids will accumulate in the cardiomyocytes. LÄS MER

  3. 12. About hyaluronan in the hypertrophic heart : studies on coordinated regulation of extracellular matrix signalling

    Författare :Urban Hellman; Anders Waldenström; Stellan Mörner; Anna Engström-Laurent; Lena Jonasson; Umeå universitet; []
    Nyckelord :hyaluronan; hyaluronan synthases; gene expression; extracellular matrix; cardiac hypertrophy; rat wistar; male ; cardiomyocytes; growth factors; fibroblasts; microvesicles; exosomes; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Background. Myocardial hypertrophy is a risk factor for cardiovascular morbidity and mortality. Independent of underlying disease, the cardiac muscle strives in different ways to compensate for an increased workload. This remodelling of the heart includes changes in the extracellular matrix which will affect systolic and diastolic cardiac function. LÄS MER

  4. 13. Signal transduction in restenosis and myocardial protection by hyperoxia

    Författare :Arno Ruusalepp; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neointima; inflammation; NF-kappaB; preconditioning; MAPK; nitric oxide;

    Sammanfattning : Ischemic heart disease is a major cause of morbidity and mortality in the western world. Revascularization of ischemic myocardium is essential for cell survival, and is performed by thrombolysis, percutaneous transluminal coronary angioplasty (PTCA) and by coronary artery bypass grafting. LÄS MER