Sökning: "membrane targeting"

Visar resultat 21 - 25 av 159 avhandlingar innehållade orden membrane targeting.

  1. 21. Membrane Protein Biogenesis in Saccharomyces cerevisiae

    Författare :Johannes Reithinger; Gunnar von Heijne; Richard Zimmermann; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Sammanfattning : Membranes are hydrophobic barriers that define the outer boundaries and internal compartments of living cells. Membrane proteins are the gates in these barriers, and they perform vital functions in the highly regulated transport of matter and information across membranes. LÄS MER

  3. 22. Protein production in the E. coli cell envelope

    Författare :Thomas Baumgarten; Jan-Willem de Gier; Dirk-Jan Scheffers; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; E. coli; protein biogenesis; recombinant proteins; membrane proteins; secretory proteins; protein displays; outer membrane vesicles; Biochemistry; biokemi;

    Sammanfattning : Proteins fulfil essential functions in every cell and malfunctioning proteins are often the cause of diseases. On the other hand, proteins like antibody fragments or hormones can be used to treat diseases. LÄS MER

  4. 23. Lactobacillus mediated targeting of gastrointestinal pathogens

    Författare :Kasper Krogh Andersen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The mucosal membranes of the gastrointestinal, genitourinary and respiratory tract are the main targets for infection in the human body and are repeatedly challenged by pathogens. Passive immunization using delivery of antibodies at the mucosal membrane may thus provide a new first line of defense against these pathogens. LÄS MER

  5. 24. Theranostic Targeting of GRPR and PSMA in Prostate Cancer

    Författare :Ayman Abouzayed; Anna Orlova; Ulrika Rosenström; Anzhelika Vorobyeva; Bogdan Mitran; Cristina Müller; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; gastrin-releasing peptide receptor GRPR ; prostate-specific membrane antigen PSMA ; nuclear medicine; molecular imaging; radiotracers; theranostics; Farmaceutisk vetenskap; Pharmaceutical Science; Oncology; Onkologi;

    Sammanfattning : This thesis is based on five original articles that investigated the theranostics of prostate cancer by gastrin-releasing peptide receptor (GRPR) and prostate-specific membrane antigen (PSMA) targeting. GRPR and PSMA are two extensively evaluated prostate cancer cell markers due to their overexpression in the majority of prostate cancer samples. LÄS MER

  7. 25. Biophysical studies of membrane associated biomolecular interactions

    Författare :Weihua Ye; Arnold Maliniak; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Membrane associated interactions play important roles in various biological processes. The aim of this thesis is to study two types of membrane associated interactions by using biophysical methods, particularly NMR. First, the interaction of a targeting peptide and a receptor attached to membrane has been studied. LÄS MER