Sökning: "membrane lipids analysis"

Visar resultat 21 - 25 av 42 avhandlingar innehållade orden membrane lipids analysis.

  1. 21. Towards specific quantification of exosomes using surface-based sensing

    Författare :Deborah Rupert; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; label-free; surface plasmon resonance.; exosome; binding rate; antibody; concentration; nanoparticle tracking analysis; quantification; liposome; cluster of differentiation 63 CD63 ; diffusion; specific detection; mass transport limited conditions; extracellular vesicles; surface-based biosensor;

    Sammanfattning : When exosomes were first observed in 1967, they were believed to be cell debris until extensive studies demonstrated key biological functionalities related to their composition and formation mechanism. Exosomes are nanometer-sized lipid vesicles of endocytic origin, with a membrane consisting of lipids and proteins and encapsulating a cargo composed of soluble proteins and genetic material. LÄS MER

  3. 22. Studies on the structure and biogenesis of membrane proteins from the green alga Chlamydomonas reinhardtii

    Författare :Ghasem Nurani; Max Möller; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi;

    Sammanfattning : The green alga unicellular Chlamydomonas reinhardtii has been used for many years as a model system in the area of photosynthesis. Therefore, the C. reinhardtii chloroplast has been the subject of many studies. In contrast, the mitochondria have received less attention. LÄS MER

  4. 23. Antimicrobial polypeptides and lipids as a part of innate defense mechanism of fish and human fetus

    Författare :Gudmundur Bergsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Animals are constantly threatened by vast numbers of microbes and have consequently evolved an array of strategies to prevent microbial invasion. In this thesis, I have studied natural antimicrobial lipids and polypeptides associated with immediate host defense. LÄS MER

  5. 24. Development and Evaluation of Preparation Methods for the Analysis of Cell Membranes Using Time-of-Flight Secondary Ion Mass Spectrometry

    Författare :Jakob Malm; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; salt; cryofixation; TOF-SIMS; supported phospholipid bilayer; freeze drying; vacuum; cells; POPC; glutaraldehyde;

    Sammanfattning : The aim of this work was to evaluate and develop methods for preparing dry samples for TOF-SIMS analysis of cell membranes. For correct interpretation of the analysis data, an understanding of the effects that the preparation method has on the morphology and chemical structure of the sample must first be obtained. LÄS MER

  7. 25. Interrogation of drug effects on the lipid composition of single cells and Drosophila brain using ToF-SIMS imaging

    Författare :Thuy Mai Hoang Philipsen; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Drosophila melanogaster; Keywords: Mass spectrometry imaging; PC12 cell.; ToF-SIMS; zinc deficiency; lipid change; methylphenidate; cocaine; cognition; omega-3 and 6- fatty acids;

    Sammanfattning : Lipids are essential for all living organisms on Earth. The most important function of lipids is that they act as the building blocks of cellular membranes. Lipids consist of polar head groups and non-polar tail groups and assemble into bilayer structures to create cell and organelle membranes. LÄS MER