Sökning: "molecular modeling proteins"
Visar resultat 1 - 5 av 82 avhandlingar innehållade orden molecular modeling proteins.
1. Major Intrinsic Proteins - Structure, function, interactions
Sammanfattning : Major intrinsic proteins, also referred to as aquaporins (AQPs) are localized in membranes of all domains of life to increase the permeability to water or other small, polar molecules. Several monophyletic groups can be discerned in this large and divergent protein superfamily. LÄS MER
2. Stochastic modeling of motor proteins
Sammanfattning : Motor proteins are microscopic biological machines that convert chemical energy into mechanical motion and work. They power a diverse range of biological processes, for example the swimming and crawling motion of bacteria, intracellular transport, and muscle contraction. LÄS MER
3. Modeling of voltage-gated ion channels
Sammanfattning : The recent determination of several crystal structures of voltage-gated ion channels has catalyzed computational efforts of studying these remarkable molecular machines that are able to conduct ions across biological membranes at extremely high rates without compromising the ion selectivity. Starting from the open crystal structures, we have studied the gating mechanism of these channels by molecular modeling techniques. LÄS MER
4. Modeling and simulation of intrinsically disordered proteins
Sammanfattning : This work is primarily about the development, validation and application of computer simulation models for intrinsically disordered proteins, both in solution and in the presence of uniformly charged, ideal surfaces. The models in question are either coarse-grained or atomistic in nature, and their applications are dependent on the specific purpose of each study. LÄS MER
5. Molecular epidemiology approach : nested case-control studies in glioma and lymphoid malignancies
Sammanfattning : BACKGROUND: Nested case-control studies aim to link molecular markers with a certain outcome. Repeated prediagnostic samples may improve the evaluation of marker-disease associations. However, data regarding the benefit of repeated samples in such studies are sparse. LÄS MER