Sökning: "marginal zone"

Visar resultat 16 - 20 av 59 avhandlingar innehållade orden marginal zone.

1. 16. Tolerance and Immunity: Opposite Outcomes of Microbial Antigen Stimulation

   Författare :Lena Eroukhmanoff; Immunologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TLR2; Tolerance; quinoline-3-carboxamide; Anergy; Foxp3; iNOS; IFN-β; CD4 splenic DCs;

   Sammanfattning : The immune system is remarkable in many ways. It exerts immunity to defend us from foreign pathogens, while it is also responsible for maintaining tolerance to avoid autoimmune diseases and allergy. This thesis includes three separate papers concerning both tolerance and immunity. LÄS MER

3. 17. B cells in Autoimmunity : Studies of Complement Receptor 1 & 2 and FcγRIIb in Autoimmune Arthritis

   Författare :Kajsa Prokopec; Sandra Kleinau; Anna Erdei; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cells; complement receptors; fc gamma receptor IIb; autoimmune arthritis; rheumatoid arthritis; Immunology; Immunologi;

   Sammanfattning : B cells are normally regulated to prevent activation against self-proteins through tolerance mechanisms.  However, occasionally there is a break in tolerance and B cells can become self-reactive, which might lead to the development of autoimmune disease. LÄS MER

4. 18. Ventilation distribution in the lung periphery measured by inert gas washout : influence of increased gravity, anti-G suit pressure, body posture, and breathing pattern

   Författare :Mikael Grönkvist; Göran Hedenstierna; Linköpings universitet; []
   Nyckelord :acceleration; anti-G suit; body posture; cdi; dcdi; human centrifuge; He; hypergravuty; lung; multiple-breath washout; single-breath washout; SF 6; standing; supune; trapped gas; ventilation distribution; MEDICINE; MEDICIN;

   Sammanfattning : The lung is highly sensitive to forces of gravity and acceleration, and to surrounding pressures. This thesis aimed to assess the effects on ventilation distribution in peripheral lung units when changing the direction or magnitude of the gravitational vector and when compressing the lower body half with an anti-G suit (AGS). LÄS MER

5. 19. Regulation of B cell responses to modified self

   Författare :Emilie Grasset; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The immune system needs to be efficient to protect organisms from invading pathogens. Lymphoid organs such as the spleen and lymph nodes are needed to initiate the response. LÄS MER

7. 20. Urban Building Energy Modeling for Retrofit Scenarios : Development, Calibration, Validation and Implementation for Swedish Residential Buildings

   Författare :Fatemeh Johari; Joakim Widén; Darren Robinson; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Urban building energy modeling; Urban building energy retrofit; Urban energy system; Urban energy planning; Energy performance certificate; Energy efficiency; low-energy cities; Engineering Science with specialization in Civil Engineering and Built Environment; Teknisk fysik med inriktning mot byggteknik och byggd miljö;

   Sammanfattning : The necessity for an accelerated transition of urban energy systems and, in particular, the building sector toward energy efficiency and carbon neutrality poses new challenges to planning and retrofitting existing buildings. To cope with these challenges, so-called urban building energy models (UBEMs) have been introduced for quantifying the energy demand in the building sector, identifying the hot spots of energy use and suggesting scenarios for retrofitting the buildings. LÄS MER