Sökning: "loss of heterozygozity"

Hittade 2 avhandlingar innehållade orden loss of heterozygozity.

  1. 1. Genetic alterations in Scandinavian neuroblastoma tumors

    Författare :Katarina Ejeskär; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; loss of heterozygozity; deletion; 1p; 3p; CDC2L1; TP73; CORT; FHIT;

    Sammanfattning : The results presented here derive from our efforts to find genes and chromosomal regions of interest in the formation and progression of the childhood tumor neuroblastoma.Neuroblastoma is the most common extracranial solid tumor of childhood. LÄS MER

  3. 2. Transcription Associated Recombination in Mammalian Cells

    Författare :Linda Savolainen; Thomas Helleday; Andres Aguilera; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Biologi; molekylärgenetik; Molecular Genetics;

    Sammanfattning : There is increasing evidence that the movement of the transcription machinery through DNA has profound effects on the genomic stability. One such example is a phenomenon known as Transcription Associated Recombination (TAR). Transcription enhances recombination levels to a high degree in all organisms studied, from bacteria to mammals. LÄS MER