Sökning: "3p"

Visar resultat 1 - 5 av 67 avhandlingar innehållade ordet 3p.

  1. 1. Genetic alterations in Scandinavian neuroblastoma tumors

    Författare :Katarina Ejeskär; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; loss of heterozygozity; deletion; 1p; 3p; CDC2L1; TP73; CORT; FHIT;

    Sammanfattning : The results presented here derive from our efforts to find genes and chromosomal regions of interest in the formation and progression of the childhood tumor neuroblastoma.Neuroblastoma is the most common extracranial solid tumor of childhood. LÄS MER

  3. 2. Molecular mechanisms in cervical carcinogenesis : Studies of clonality, somatic genetic alterations and human papillomavirus variants in cervical pre-invasive and invasive cancer

    Författare :Zhongmin Guo; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cervical cancer; CIN; clonality; X-chromosome inactivation; LOH; HPV; chromosome 3p; chromosome 6; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : Cervical cancer derives from a series of pre-invasive cervical neoplastic lesions termed CIN I-III (Cervical Intraepithelial Neoplasia) via typical multiple-step processes. In contrast to premalignant disorders in other organs, different degrees of CIN possess a distinct biological behaviour where a proportion spontaneously regress or persist, whereas some progress to invasive cancer. LÄS MER

  4. 3. Low-temperature District Heating : Various Aspects of Fourth-generation Systems

    Författare :Helge Averfalk; Sven Werner; Brian Elmegaard; Högskolan i Halmstad; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; District heating; low temperature; three-pipe systems; 4GDH-3P; District heating; low temperature; three-pipe systems; 4GDH-3P;

    Sammanfattning : With decreasing heat demand and less availability of high-temperature heat supply in future energy systems, the current district heating systems may experience increased competition on the heat market. A viable option to mitigate increasing competition is to operate systems with lower temperature levels, and the most conceivable way to achieve lower temperature levels is to decrease return temperatures. LÄS MER

  5. 4. Delection mapping of human 3p in major epithelial types of cancer and fine localization of candidate tumor suppressor genes

    Författare :Jian Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Tumor suppressor gene; epithelial carcinoma; human chromosome 3p;

    Sammanfattning : Allele loss and deletion mapping using microsatellite markers and the detection of homozygous deletions represented until now the most powerful method to localize potential TSGs. Loss of heterozygosity (LOH) involving several chromosome 3p regions accompanied by chromosome 3p deletions are detected in almost 100% of renal cell carcinoma (RCC), small (SCLCs) and more than 90% of non-small (NSCLC) cell lung cancers. LÄS MER

  7. 5. Molecular genetic aspects of renal cell carcinoma development

    Författare :Andrei Alimov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Kidney tumor; RCC; LOH; CGH; SKY; PTEN; chromosome 3p; chromosome 10q; chromosome 14q;

    Sammanfattning : Renal cell carcinoma (RCC) is the most common tumor of the renal parenchyma. The aim of this study was to further characterize known as well as new genetic abnormalities in a clinical material of RCC, as well as in established cell lines to gain more information about etiological and progression factors. LÄS MER