Sökning: "lipid dynamics"

Visar resultat 21 - 25 av 119 avhandlingar innehållade orden lipid dynamics.

  1. 21. Interaction of Calcium Ions with Lipid Membranes

    Författare :Baharan Ali Doosti; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; phospholipid bilayer membrane; membrane dynamics; micromanipulation; calcium ions; cell migration.; membrane nanotube; membrane tubular protrusions; calcium ion concentration gradient; membrane bending; giant unilamellar vesicle;

    Sammanfattning : Bilayer membranes enclose and shield the biological cell and its inner compartments, as well as the tubular networks that exist within and between the cells. Due to their fluidic nature, the membranes are incredibly dynamic and flexible, which allows them to bend, reshape and fuse in response to mechanical and chemical stimuli within their natural microenvironments. LÄS MER

  3. 22. Structure, dynamics and lipid interaction of membrane-associated proteins

    Författare :Pontus Pettersson; Lena Mäler; Jason Schnell; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biophysics; biofysik;

    Sammanfattning : A research topic within the field of molecular biophysics is the structure-function relationship of proteins. Membrane proteins are a large, diverse group of biological macromolecules that perform many different and essential functions for the cell. LÄS MER

  4. 23. Water Relaxation Processes as Seen by NMR Spectroscopy Using MD and BD Simulations

    Författare :Ken Åman; Per-Olof Westlund; Arnold Maliniak; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; NMR; Stochastic Liouville Equation; Brownian Dynamics; Molecular Dynamics; Water; Relaxation; Deuterium; ESR; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi; Physical Chemistry; fysikalisk kemi;

    Sammanfattning : This thesis describes water proton and deuterium relaxation processes, as seen by Nuclear Magnetic Resonance (NMR) spectroscopy, using Brownian Dynamics (BD) or Molecular Dynamics (MD) simulations. The MD simulations reveal new detailed information about the dynamics and order of water molecules outside of a lipid bilayer. LÄS MER

  5. 24. Characterization of ATP-dependent protein dynamics under native-like conditions

    Författare :Harsha Ravishankar; Magnus Andersson; Hans Wolf-Watz; Lise Arleth; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; proteins; membrane proteins; structural dynamics; ATPases; MD simulations; X-ray scattering; FTIR spectroscopy; ATP; TR-XSS; structural biology.; Biochemistry; biokemi;

    Sammanfattning : Proteins are biological macromolecules capable of accelerating biochemical reactions. To accomplish this, proteins undergo changes in their molecular structure. Advances in structural biology have resulted in ever-increasing numbers of high-resolution protein structures. LÄS MER

  7. 25. Simulating Functional Cycles and Drug Modulation in Ligand-gated Ion Channels

    Författare :Yuxuan Zhuang; Erik Lindahl; Grace Brannigan; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ion channels; molecular dynamics; markov state model; lipid modulation; nicotinic receptor; protein conformational transitions; Biophysics; biofysik;

    Sammanfattning : Understanding the intricate motions and conformational changes that govern biological processes remains a fascinating and challenging endeavor. The research presented in this thesis aims to elucidate the dynamic processes underlying biological functions, specifically focusing on the dynamics of pentameric ligand-gated ion channels (pLGICs), which play a crucial role in signal transduction within the brain. LÄS MER