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Visar resultat 11 - 15 av 48 avhandlingar som matchar ovanstående sökkriterier.

  1. 11. Congenital Recessive Ichthyosis : Studies of Gene Expressions Related to Keratinocyte Differentiation and Skin Barrier Repair

    Författare :Hanqian Zhang; Hans Törmä; Anders Vahlquist; Marie Virtanen; Mikael Ivarsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; genodermatoses; oligoarray; trancriptomics; transglutaminase-1; cornified envelope; peroxisome proliferator-activated receptor δ; all-trans retinoic acids.; Dermatologi och venereologi; Dermatology and Venerology;

    Sammanfattning : Autosomal recessive congenital ichthyosis (ARCI) is a rare monogenetic disorder characterized by a defective skin barrier, hyperkeratosis, and dry, scaly skin. It affects keratinocyte differentiation and is caused by mutations in any of at least 12 genes believed to control the formation of ω-O-acylceramide and the corneocyte lipid envelope (CLE): ABCA12, ALOXE3, ALOX12B, CERS3, CYP4F22, ELOVL4, LIPN, NIPAL4, PNPLA1, SDR9C7, SLC27A4, and TGM1. LÄS MER

  3. 12. Keratinocyte differentiation. Involvement of the growth hormon (GH)/insulinlike growth factor1 (IGFI) axis and IGF1 post receptor signaling

    Författare :Elisabeth Björntorp Mark; Göteborgs universitet; []
    Nyckelord :IGF1R; GH; Id1; keratinocytes; psoriasis;

    Sammanfattning : At cellular level, little is known about the genes that regulate keratinocyte differentiation andproliferation. Psoriasis is regarded as a T-cell mediated inflammatory disease with hyperproliferativekeratinocytes. LÄS MER

  4. 13. Effect of surface characteristics on cellular adherence and activity

    Författare :Marjan Dorkhan; Malmö högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bacteria; microbial biofilm; dental implant; streptococci; oral bacteria; salivary pellicle; early colonizers; titanium oxide; microbial activity; oral keratinocytes; gingival fibroblasts; cell attachment; surface modification; anodic oxidation; anatase;

    Sammanfattning : Ersättning av förlorade tänder med tandimplantat är numera en vanlig behandlingsmetod med generellt goda resultat. Antalet implantatsystem på den internationella marknaden har ökat kraftigt under senare år. LÄS MER

  5. 14. Understanding the role of regulatory RNAs in human skin wound healing

    Författare :Letian Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human skin wound healing is characterized by four phases in a timely manner, including hemostasis, inflammation, proliferation, and remodeling. Various cell types are involved in the biological process. LÄS MER

  7. 15. Keratinocytes and Adipose-derived mesenchymal stem cells : The heir and the spare to regenerative cellular therapies for difficult-to-heal skin wounds

    Författare :Hady Shahin; Ahmed Taher Elserafy; Moustafa Elmasry; Folke Sjöberg; Ingrid Steinvall; Daniel Nowinski; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Keratinocytes; ATMP; Bio-production; Adipose-derived mesenchymal stem cells; Wound healing;

    Sammanfattning : Cell-based therapy is considered as Advanced Therapy Medicinal Product, (ATMP), which had increasingly stricter regulations in the last decade. The cells must be produced according to the ‘Guidelines on Good Manufacturing Practice (GMP) specific to Advanced Therapy Medicinal Products’, adopted by the European Medicines Agency (EMA). LÄS MER