Sökning: "Id1"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet Id1.

  1. 1. Cell cycle genes in chondrosarcoma. Involvement of the Id1 and p16 pathways

    Författare :Julia Asp; Göteborgs universitet; []
    Nyckelord :chondrosarcoma; articular chondrocytes; cell cycle; p16; Id1; helix-loop-helix;

    Sammanfattning : Chondrosarcoma is a malignant, cartilaginous tumour arising from bone. The wide variationin morphology, behaviour and clinical outcome raise the question whether chondrosarcomasare several different but closely related tumours rather than a single entity. LÄS MER

  3. 2. Keratinocyte differentiation. Involvement of the growth hormon (GH)/insulinlike growth factor1 (IGFI) axis and IGF1 post receptor signaling

    Författare :Elisabeth Björntorp Mark; Göteborgs universitet; []
    Nyckelord :IGF1R; GH; Id1; keratinocytes; psoriasis;

    Sammanfattning : At cellular level, little is known about the genes that regulate keratinocyte differentiation andproliferation. Psoriasis is regarded as a T-cell mediated inflammatory disease with hyperproliferativekeratinocytes. LÄS MER

  4. 3. Not just a pipe's dream : plumbing the contribution of cell diversity to oesophageal homeostasis

    Författare :David Grommisch; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Epithelial barrier tissues like the skin, intestine, and oesophagus form a physical barrier that protects our body from external threats. To accurately fulfil their function, epithelial barriers are subject to constant epithelial cell renewal throughout our lifespan. LÄS MER

  5. 4. An exPADItion for citrullination in the developing hair follicle

    Författare :Kim Vikhe Patil; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : During epidermal development, to assure proper tissue structure, highly complex transcriptional networks interact within the stem cell compartments of the epidermis and hair follicles (HFs) to balance the choice between self-renewal or differentiation. The full characterisation of the protein profiles resulting from those transcriptional networks, within the compartments of the HF, remains, however, incomplete. LÄS MER

  7. 5. TGFβ Signal Transduction in Endothelial Cells

    Författare :Gudrun Valdimarsdóttir; Peter ten Dijke; Carl-Henrik Heldin; Christer Betsholtz; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Cellbiologi; Cell biology; Cellbiologi;

    Sammanfattning : Transforming growth factor β (TGFβ) is a multifunctional cytokine that is involved in many biological effects, such as proliferation, migration, differentiation and cell survival. TGFβ regulates cellular responses by binding to a heteromeric complex of type I and type II serine/threonine kinase receptors. LÄS MER