Sökning: "peroxisome proliferator-activated receptor δ"

Hittade 3 avhandlingar innehållade orden peroxisome proliferator-activated receptor δ.

  1. 1. Peroxisome proliferator-activated receptor delta : regulation of skeletal muscle metabolism

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Molecular Medicine and Surgery

    Författare :David Kitz Krämer; Karolinska Institutet.; Karolinska Institutet.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peroxisome Proliferator-Activated Receptor PPAR 4 insulin sensitivity; insulin action; human skeletal muscle; primary cultured muscle cells; lipid-metabolism; glucose metabolism; AMP activated protein kinase AMPK ; Type 2 Diabetes Mellitus;

    Sammanfattning : Peroxisome Proliferator-Activated Receptor (PPAR) δ is a nuclear transcription factor which has been implicated in the regulation of lipid metabolism in skeletal muscle. In addition to the postural and locomotive functions of skeletal muscle, this organ has a major impact role on whole body metabolism. LÄS MER

  2. 2. Congenital Recessive Ichthyosis Studies of Gene Expressions Related to Keratinocyte Differentiation and Skin Barrier Repair

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Hanqian Zhang; Hans Törmä; Anders Vahlquist; Marie Virtanen; Mikael Ivarsson; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; genodermatoses; oligoarray; trancriptomics; transglutaminase-1; cornified envelope; peroxisome proliferator-activated receptor δ; all-trans retinoic acids.; Dermatologi och venereologi; Dermatology and Venerology;

    Sammanfattning : Autosomal recessive congenital ichthyosis (ARCI) is a rare monogenetic disorder characterized by a defective skin barrier, hyperkeratosis, and dry, scaly skin. It affects keratinocyte differentiation and is caused by mutations in any of at least 12 genes believed to control the formation of ω-O-acylceramide and the corneocyte lipid envelope (CLE): ABCA12, ALOXE3, ALOX12B, CERS3, CYP4F22, ELOVL4, LIPN, NIPAL4, PNPLA1, SDR9C7, SLC27A4, and TGM1. LÄS MER

  3. 3. Sarcoidosis : expression of cell regulatory markers and the influence of patient phenotype on bronchoalveolar lavage cell differential counts

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Medicine, Solna

    Författare :Muntasir Abo Al Hayja; Karolinska Institutet.; Karolinska Institutet.; [2020]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Sarcoidosis is a systemic inflammatory disease that can affect almost any organ, but the respiratory system is affected in more than 90% of the cases. To elicit an immune response, an antigen(s) is processed by antigen-presenting cells (APCs), e.g. LÄS MER