Sökning: "iron-sulfur clusters"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden iron-sulfur clusters.

1. 1. Isoforms of mammalian glutaredoxin 2

   Författare :Christoph Hudemann; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Iron-sulfur proteins are characterized by the presence of iron-sulfur clusters containing sulfide linked iron centers in variable oxidation states. Glutaredoxins (Grx) are, among other redoxins, increasingly recognized to be involved at the interface between redox regulation, iron metabolism and iron-cluster biosynthesis. LÄS MER

3. 2. Formation of Thiolated Nucleosides in tRNA in Salmonella enterica serovar typhimurium

   Författare :Hans Lundgren; Glenn Björk; Charles Lauhon; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; : tRNA; modified nucleosides; thiolation; sulfur metabolism; Salmonella; Molecular biology; Molekylärbiologi;

   Sammanfattning : The presence and synthesis of transfer RNA (tRNA) is highly conserved in all organisms and a lot of genetic material is dedicated to its synthesis. tRNA contains a large number of modified nucleosides and several diverse functions have been found but much about their function is still unknown. LÄS MER

4. 3. The evolution of respiratory chain complex I from smaller functional modules

   Författare :Vamsi Moparthi; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hyf; Hyc; Membrane bound hydrogenases; NADH:quinone oxidoreductase; Mrp antiporter; 16S rRNA;

   Sammanfattning : NADH:quinone oxidoreductase, or complex I, is a large membrane bound enzyme in the respiratory chain of living organisms, that has evolved from the combination of smaller functional building blocks. The enzyme has a conserved core structure, comprising 14 protein subunits: Seven subunits protrude from the membrane and contain a flavin and eight iron-sulfur clusters. LÄS MER

5. 4. NADH:quinone oxidoreductase: the black box of the respiratory chain

   Författare :Robert Roth; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NADH:quinone oxidoreductase; Complex I; electron transport; membrane protein; ubiquinone; respiratory chain; respiration; metabolism; Metabolism; Biokemi; Biochemistry;

   Sammanfattning : Complex I or NADH:quinone oxidoreductase the largest, most complex and least understood of the five membrane-bound enzyme complexes constituting the mitochondrial respiratory chain. The enzyme is present in all types of organisms, from bacteria to mammals. LÄS MER

7. 5. The Membrane-Spanning Domain of Complex I Investigated with Fusion Protein Techniques

   Författare :Maria Trane; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NuoN; NuoM; NuoL; covalent bound heme; Bacillus subtilis; Escherichia coli; membrane protein; His-tag; Cytochrome c; NADH:quinone oxidureductase; fusion protein;

   Sammanfattning : NADH:quinone oxidoreductase, or complex I, is a large, complex and poorly understood bioenergetic enzyme in the respiratory chain of living organisms. The enzyme has a conserved core structure, comprising fourteen protein subunits: Seven subunits protrude from the membrane and contain a flavin prosthetic group and eight iron-sulfur clusters that guide electrons from the oxidation of NADH towards the quinone binding site(s). LÄS MER