Sökning: "intestinal ischemia"

Visar resultat 21 - 25 av 30 avhandlingar innehållade orden intestinal ischemia.

  1. 21. Mesentric hemodynamics and effects of angiotensin II during circulatory stress

    Författare :Mats Laesser; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Renin-angiontensin system; angiotensin II; intestines; hemodynamics; perfusion; hemorrhage; hypovolemia; endotoxemia;

    Sammanfattning : Mesenteric hypoperfusion and ischemia is considered to be deleterious to the intestinal mucosal barrier function and it is suggested that the renin-angiotensin system plays a pivotal role in the regulation of mesenteric perfusion.The present thesis examines the effects of the specific AT1 receptor blocker candesartan on mesenteric hemodynamics during acute hypovolemia and endotoxinemia. LÄS MER

  3. 22. Microdialysis monotoring of ischemic metabolism in splanchnic organs : liver and intesine

    Författare :Johan Ungerstedt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Monitoring vascular complications in the liver and the intestine is of great importance. Ischemia in these organs is life threatening and may cause organ dysfunction, sepsis and multiple organ failure. Aim: The present thesis explores the use of microdialysis as a monitoring technique in the liver and the intestine. LÄS MER

  4. 23. Intraperitoneal microdialysis : technique and results

    Författare :Kjell Jansson; Lars Norgren; Carl-Henrik Nordström; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; kirurgi; Surgery; Kirurgi; Kirurgi; Surgery;

    Sammanfattning : Microdialysis has recently developed from a laboratory research method of animals to a useful clinical tool to evaluate parameters suggesting tissue ischemia. It is now used in neurosurgery, plastic surgery and liver transplantation. LÄS MER

  5. 24. The Foxf2 gene in development and disease

    Författare :Azadeh Reyahi; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Foxf2; Pericyte; brain development; stroke;

    Sammanfattning : The Foxf2 gene in development and disease Azadeh Reyahi Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE 405 30, Göteborg, Sweden Abstract In this thesis I present our recent data on the involvement and the mechanism of action of the forkhead transcription factor Foxf2 in development of the brain microvasculature, formation of the blood-brain barrier, control of the intestinal stem cell niche, and fusion of the secondary palate. The potential clinical signifi- cance of these findings is strengthened by a correlation between Foxf2 expres- sion and intestinal adenoma formation, and by association between genetic vari- ants in human FOXF2 and incident stroke. LÄS MER

  7. 25. Necrotizing enterocolitis : imaging and risk assessment

    Författare :Elena Palleri; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Despite decades of research on necrotizing enterocolitis (NEC), no major finding has improved the mortality and morbidity of the disease or changed the clinical management. The exact pathogenesis remains unclear, but several factors such as immature intestinal immunity, impaired bowel microcirculation, enteral nutrition and abnormal microbiota may play important roles. LÄS MER