Sökning: "nicotinamide"

Visar resultat 1 - 5 av 31 avhandlingar innehållade ordet nicotinamide.

  1. 1. The mode of action of the radiosensitizing analogs metoclopramide and nicotinamide

    Författare :Anders Olsson; Lund Wallenberg Neurocentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; medical instrumentation; metoclopramide; nicotinamide; apoptosis; radiosensitization; NAD; benzamide; DNA repair; Clinical physics; tomography; radiology; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering;

    Sammanfattning : This thesis provides the first attempt to study the nicotinamides and benzamides from a mode of action point of veiw. Understanding the effects on DNA repair, cell cycle control (proliferation) and cell death from these agents and in combination with ionizing radiation, provides a new opportunity to logically develop better approaches to sensitize already existing therapies via for example induction of apoptosis or inhibition of DNA repair. LÄS MER

  3. 2. Mitochondrial nicotinamide nucleotide transhydrogenase : studies of the mammalian and plant enzymes with special reference to the beef heart and potato transhydrogenases

    Författare :Elisabeth Carlenor; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  4. 3. Mitochondrial nicotinamide nucleotide transhydrogenase : structure and energy-linked functions of purified and membrane-bound transhydrogenase from beef heart

    Författare :Bengt L. Persson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  5. 4. Mitochondrial nicotinamide nucleotide transhydrogenase : kinetics and functional relationship to the energy-conserving system of the respiratory chain

    Författare :Jan Rydström; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  7. 5. ARCON in experimental and clinical radiotherapy

    Författare :Ana Maria Rojas Callejas; Björn Zackrisson; René-Olivier Mirimanoff; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; ARCON; tumours; normal tissues; radiosensitization; carbogen; nicotinamide; repair inhibition; therapeutic gain; rodents; humans; Onkologi; Oncology; Onkologi; onkologi; Oncology;

    Sammanfattning : xHypoxia and repopulation of tumour clonogens are two important determinants of treatment outcome in radiotherapy. In general clinical evidence indicates that loco-regional control may be reduced with long overall treatment times and for tumours with low pre-treatment levels of oxygen. LÄS MER