Sökning: "high-grade"
Visar resultat 1 - 5 av 207 avhandlingar innehållade ordet high-grade.
1. High-grade spondylolisthesis in young patients : Long-term results of in situ fusion
Sammanfattning : The purpose of this long-term follow-up of 38 of 40 consecutive patients was to evaluate the results of uninstrumented in situ fusion for high-grade isthmic spondylolisthesis three decades after surgery. The mean age at surgery was 14 (range 9-24) years. LÄS MER
2. Prognostic Biomarkers and Target Proteins for Treatment of High-grade Gliomas
Sammanfattning : The survival for high-grade glioma patients is poor and the treatment may cause severe side effects. A common obstacle in the treatment is chemoresistance. To improve the quality of life and prolong survival for these patients prognostic biomarkers and new approaches for chemotherapy are needed. LÄS MER
3. The Swedish Infant High-grade Reflux Trial - and a Focus group study of parents’ experiences
Sammanfattning : Background: Vesicoureteral reflux (VUR) is a pathological back-flow of urine from the bladder to the ureter and renal pelvis. VUR is associated with an increased risk of urinary tract infections (UTI) and renal damages. LÄS MER
4. Modeling and investigations of high-grade glioma to understand tumorigenesis and heterogeneity
Sammanfattning : Glioblastoma (GBM) is the most common primary malignant brain tumor. As per 2021 WHO classification, the corresponding diagnosis in children is called diffuse pediatric-type high-grade glioma (pHGG). In both cases tumors are histone 3 (H3) and isocitrate dehydrogenase 1/2 (IDH1/2) wildtype (wt). LÄS MER
5. Cell-based models for studying paediatric high-grade gliomas
Sammanfattning : Brain tumours are the largest group of solid tumours in children and accounts for most cancer-related deaths. Astrocytoma is the largest group, representing almost half of the brain tumours, where high-grade glioma is one of the most devastating forms with very poor prognosis due to lack of efficient treatments. LÄS MER