Sökning: "xenograft tumour"
Visar resultat 1 - 5 av 17 avhandlingar innehållade orden xenograft tumour.
1. Cell-based models for studying paediatric high-grade gliomas
Sammanfattning : Brain tumours are the largest group of solid tumours in children and accounts for most cancer-related deaths. Astrocytoma is the largest group, representing almost half of the brain tumours, where high-grade glioma is one of the most devastating forms with very poor prognosis due to lack of efficient treatments. LÄS MER
2. The involvement of gangliosides in growth and migration of human glioblastoma cells
Sammanfattning : Human glioblastoma is a primary brain tumour with a bad prognosis. One major contributing factor is that the tumour grows in an infiltrative way. Single tumour cells, undetectable with today's techniques, invade the brain and escape therapy. LÄS MER
3. Aspects on Diagnosis and Treatment of Gastrointestinal Neuroendocrine Tumours
Sammanfattning : Aspects on Diagnosis and Treatment of Gastrointestinal Neuroendocrine Tumours Background. Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) originate from endocrine cells of the intestinal mucosa and pancreas. LÄS MER
4. The significance of urokinase-type plasminogen activator (u-PA) in tumour growth and Linomide-induced upregulation of u-PA's endogenous inhibitor PAI-2
Sammanfattning : The progressive process of tumour invasion and generation of metastases is the primary cause of death for most patients with cancer. Some of the regulatory components of this progressive process are adhesion, migration, and proteolysis. LÄS MER
5. Development of individualized surgical treatments for malignant melanoma
Sammanfattning : Background: Cutaneous melanoma is a malignancy with an increasing incidence worldwide, especially in northern Europe. The aim of this thesis is to scrutinize the results achieved by traditional surgery and the opportunities offered by translational research for the more advanced stages of the disease. LÄS MER